ArticleBMC bioinformatics2008
mtDNAmanager: a Web-based tool for the management and quality analysis of mitochondrial DNA control-region sequences.
Article in BMC bioinformatics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Mitochondrial Haplogroup Classification of Ancient DNA Samples Using Haplotracker.BioMed research international · 2022Article
- From Forensics to Clinical Research: Expanding the Variant Calling Pipeline for the Precision ID mtDNA Whole Genome Panel.International journal of molecular sciences · 2021Article
- Massively parallel sequencing of human skeletal remains in Vietnam using the precision ID mtDNA control region panel on the Ion S5™ system.International journal of legal medicine · 2021Article
- A benchmarking of human mitochondrial DNA haplogroup classifiers from whole-genome and whole-exome sequence data.Scientific reports · 2021Article
- Development of a NovelFrontiers in cellular and infection microbiology · 2019Article
- Article
- MitoSuite: a graphical tool for human mitochondrial genome profiling in massive parallel sequencing.PeerJ · 2017Article
- Molecular Genealogy of a Mongol Queen's Family and Her Possible Kinship with Genghis Khan.PloS one · 2016Article
- Mitochondrial DNA diversity in the African American population.Mitochondrial DNA · 2015Article
- Mitochondrial DNA variation in the Viking age population of Norway.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Article
- The Use and Effectiveness of Triple Multiplex System for Coding Region Single Nucleotide Polymorphism in Mitochondrial DNA Typing of Archaeologically Obtained Human Skeletons from Premodern Joseon Tombs of Korea.BioMed research international · 2015Article
- Breast cancer risk and genetic ancestry: a case-control study in Uruguay.BMC women's health · 2015Article
- Concept for estimating mitochondrial DNA haplogroups using a maximum likelihood approach (EMMA).Forensic science international. Genetics · 2013Article
- Haplogrouping mitochondrial DNA sequences in Legal Medicine/Forensic Genetics.International journal of legal medicine · 2012Article
- Mitochondrial haplogroups and polymorphisms reveal no association with sporadic prostate cancer in a southern European population.PloS one · 2012Article
- Forensic and genetic characterization of mtDNA from Pathans of Pakistan.International journal of legal medicine · 2011Article
- No relationship found between point heteroplasmy in mitochondrial DNA control region and age range, sex and haplogroup in human hairs.Molecular biology reports · 2011Article
- A genetic investigation of Korean mummies from the Joseon Dynasty.Molecular biology reports · 2011Article
- eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics and genotype-phenotype association studies.BMC bioinformatics · 2010Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
backgroundFor the past few years, scientific controversy has surrounded the large number of errors in forensic and literature mitochondrial DNA (mtDNA) data. However, recent research has shown that using mtDNA phylogeny and referring to known mtDNA haplotypes can be useful for checking the quality of sequence data.
resultsWe developed a Web-based bioinformatics resource "mtDNAmanager" that offers a convenient interface supporting the management and quality analysis of mtDNA sequence data. The mtDNAmanager performs computations on mtDNA control-region sequences to estimate the most-probable mtDNA haplogroups and retrieves similar sequences from a selected database. By the phased designation of the most-probable haplogroups (both expected and estimated haplogroups), mtDNAmanager enables users to systematically detect errors whilst allowing for confirmation of the presence of clear key diagnostic mutations and accompanying mutations. The query tools of mtDNAmanager also facilitate database screening with two options of "match" and "include the queried nucleotide polymorphism". In addition, mtDNAmanager provides Web interfaces for users to manage and analyse their own data in batch mode.
conclusionThe mtDNAmanager will provide systematic routines for mtDNA sequence data management and analysis via easily accessible Web interfaces, and thus should be very useful for population, medical and forensic studies that employ mtDNA analysis. mtDNAmanager can be accessed at http://mtmanager.yonsei.ac.kr.
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