ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2009
Safety of laparoscopic total mesorectal excision for low rectal cancer with preoperative chemoradiation therapy.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 46 citations in OpenAlex.
- Risk factor analysis of postoperative complications after robotic rectal cancer surgery.World journal of surgery · 2011Trial
- Effects of Neoadjuvant Radiotherapy on Postoperative Complications in Rectal Cancer: A Meta-Analysis.Journal of oncology · 2022Article
- Educational system for acquiring appropriate laparoscopic colorectal surgical skills: analysis in a Japanese high-volume cancer center.Surgical endoscopy · 2021Article
- Risk factors for outlet obstruction after laparoscopic surgery and diverting ileostomy for rectal cancer.Surgery today · 2021Article
- One-Stage Total Laparoscopic Treatment for Colorectal Cancer With Synchronous Metastasis. Is It Safe and Feasible?Frontiers in surgery · 2021Review
- Laparoscopic multivisceral resection for locally advanced colon cancer: a single-center analysis of short- and long-term outcomes.Surgery today · 2020Article
- Article
- Influence of multiple stapler firings used for rectal division on colorectal anastomotic leak rate.Surgical endoscopy · 2017Article
- Factors Influencing Difficulty of Laparoscopic Abdominoperineal Resection for Ultra-Low Rectal Cancer.Surgical laparoscopy, endoscopy & percutaneous techniques · 2017Article
- Clinical implications of preoperative chemoradiotherapy prior to laparoscopic surgery for locally advanced low rectal cancer.Molecular and clinical oncology · 2017Article
- Article
- Endoscopic evaluation of clinical response after preoperative chemoradiotherapy for lower rectal cancer: the significance of endoscopic complete response.International journal of colorectal disease · 2015Article
- Techniques and feasibility of laparoscopic extended right hemicolectomy with D3 lymphadenectomy.World journal of gastroenterology · 2014Article
- Safety and factors contributing to the difficulty of laparoscopic surgery for rectal cancer treated with preoperative chemoradiotherapy.Techniques in coloproctology · 2014Article
- Laparoscopic versus open multivisceral resection for primary colorectal cancer: comparison of perioperative outcomes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013Article
- Short-term outcomes after laparoscopic surgery following preoperative chemoradiotherapy for rectal cancer.Journal of the Korean Surgical Society · 2012Article
- Laparoscopic versus open surgery for rectal cancer after neoadjuvant chemoradiation: a matched case-control study of short-term outcomes.Surgical endoscopy · 2012Article
- Multimedia article. Lateral lymph node dissection with preoperative chemoradiation for locally advanced lower rectal cancer through a laparoscopic approach.Surgical endoscopy · 2011Article
- Learning curve for standardized laparoscopic surgery for colorectal cancer under supervision: a single-center experience.Surgical endoscopy · 2011Article
- Factors affecting difficulty of laparoscopic surgery for left-sided colon cancer.Surgical endoscopy · 2010Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTotal mesorectal excision (TME) with preoperative chemoradiation therapy is an accepted standard treatment for low rectal cancer. Although the laparoscopic approach is accepted for the treatment of colon cancer, its value for low rectal cancer is unknown. The purpose of this study was to evaluate whether preoperative chemoradiation therapy exerted an adverse influence on laparoscopic TME for low rectal cancer.
methodsWe studied 125 consecutive patients who underwent laparoscopic TME for low rectal cancer. Twenty patients with preoperative chemoradiation therapy (CRT-Lap group) were compared with 105 patients without chemoradiation therapy (non-CRT-Lap group).
resultsOperating time in the CRT-Lap group (276 min, range 160-390 min) was no different from that in the non-CRT-Lap group (263 min, range 143-456 min). The CRT-Lap group had more blood loss during the operation (70 vs. 37 ml), but mean blood loss was <100 ml. The distal tumor margin was longer in the CRT-Lap group (25.8 vs. 18.6 mm). The number of lymph node harvested did not differ between the groups (14.5 vs. 15.4). Conversion to open surgery was necessary only in one case in the non-CRT-Lap group. There was no anastomotic leakage in the CRT-Lap group, whereas three patients (3.1%) had anastomotic leakage in the non-CRT-Lap group.
conclusionLaparoscopic TME with preoperative chemoradiation therapy is a safe procedure with reasonable operating time and does not appear to pose any threat to the surgical and oncologic outcomes.
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