ArticleInfection2008
Results of a local antibiotic management program on antibiotic use in a tertiary intensive care unit in Hungary.
Article in Infection, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Interventions to improve antibiotic prescribing practices for hospital inpatients.The Cochrane database of systematic reviews · 2017Pooled it
- Systematic Review and Meta-analysis of Clinical and Economic Outcomes from the Implementation of Hospital-Based Antimicrobial Stewardship Programs.Antimicrobial agents and chemotherapy · 2016Pooled it
- Compliance with antimicrobial stewardship guidelines in surgery: an observational, multidisciplinary, cohort study.World journal of emergency surgery : WJES · 2025Observational
- Do Inpatient Antimicrobial Stewardship Programs Help Us in the Battle Against Antimicrobial Resistance?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Article
- A prospective study to evaluate antimicrobial prescribing pattern among admitted patients in hilly Himalayan region of northern India.Journal of family medicine and primary care · 2021Article
- Impact of an antibiotic stewardship programme in a surgical setting.Southern African journal of infectious diseases · 2021Article
- A behavioural approach to specifying interventions: what insights can be gained for the reporting and implementation of interventions to reduce antibiotic use in hospitals?The Journal of antimicrobial chemotherapy · 2020Article
- Evaluation of a Multidisciplinary Antimicrobial Stewardship Program in a Saudi Critical Care Unit: A Quasi-Experimental Study.Frontiers in pharmacology · 2020Article
- Review
- Antimicrobial agents' utilization and cost pattern in an Intensive Care Unit of a Teaching Hospital in South India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2016Article
- Antibiotic stewardship programmes in intensive care units: Why, how, and where are they leading us.World journal of critical care medicine · 2015Review
- Influence of an infectious diseases specialist on ICU multidisciplinary rounds.Critical care research and practice · 2014Article
- Antibiotic prescription patterns at admission into a tertiary level intensive care unit in Northern India.Journal of pharmacy & bioallied sciences · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMassive antibiotic use in intensive care units (ICU) is associated with increased microbial resistance. Therefore avoiding unneccesary antibiotic usage is essential. To achieve a more considered antibiotic prescribing practice, a new antibiotic policy was implemented at our ICU. In this paper, we evaluated the impact of this intervention, and described the aetiology and incidence of blood stream infections and selected antibiotic-resistant pathogens. MATERIALS AND
methodsIn November 2002, a local antibiotic management program (LAMP) was implemented. This included a new infectious diseases specialist consultation service and restricted authorisation to prescribe antibiotics. The effect on ward-level antibiotic use was examined by segmented regression analysis. Patient, ICU and microbiology data were also recorded and compared before and after policy implementation.
resultsThe patient populations and the subsequent mortality rate were comparable before and after the implementation of the policy. Total antibiotic consumption was markedly reduced from 162.9 to 101.3 defined daily dose (DDD) per 100 patients, and per day (DDD per 100 patient-days). This was mainly accounted for a reduction in the use of quinolones, aminoglycosides, glycopeptides, metronidazol, carbepenems and third generation cephalosporins.
conclusionThis study has confirmed that establishing a targeted LAMP, based on close co-operation between intensive care physicians and infectious disease specialists together with a restricted prescribing authority, can reduce the use of antibiotics.
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19011742What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.