ArticleApplied and environmental microbiology2009
Bioinformatic and expression analyses of genes mediating zinc homeostasis in Nostoc punctiforme.
Article in Applied and environmental microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 27 citations in OpenAlex.
- Effects of zinc toxicity on the nitrogen-fixing cyanobacterium Anabaena sphaerica-ultastructural, physiological and biochemical analyses.Environmental science and pollution research international · 2021Article
- A DedA Family Membrane Protein in Indium Extrusion inFrontiers in microbiology · 2021Article
- Biosorption of Copper in Swine Manure UsingFrontiers in microbiology · 2021Article
- Cyanobacterial Catalase Activity Prevents Oxidative Stress Induced by Pseudomonas fluorescens DUS1-27 from Inhibiting Brassica napus L. (canola) Growth.Microbes and environments · 2018Article
- The Response of a 16S Ribosomal RNA Gene Fragment Amplified Community to Lead, Zinc, and Copper Pollution in a Shanghai Field Trial.Frontiers in microbiology · 2018Article
- Role of Phosphate Transport System Component PstB1 in Phosphate Internalization by Nostoc punctiforme.Applied and environmental microbiology · 2016Article
- Extreme zinc tolerance in acidophilic microorganisms from the bacterial and archaeal domains.Extremophiles : life under extreme conditions · 2013Article
- Response of P. aeruginosa E(1) gene expression to cadmium stress.Current microbiology · 2012Article
- Characterization of the response to zinc deficiency in the cyanobacterium Anabaena sp. strain PCC 7120.Journal of bacteriology · 2012Article
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinc homeostasis was investigated in Nostoc punctiforme. Cell tolerance to Zn(2+) over 14 days showed that ZnCl(2) levels above 22 microM significantly reduced cell viability. After 3 days in 22 microM ZnCl(2), ca. 12% of the Zn(2+) was in an EDTA-resistant component, suggesting an intracellular localization. Zinquin fluorescence was detected within cells exposed to concentrations up to 37 microM relative to 0 microM treatment. Radiolabeled (65)Zn showed Zn(2+) uptake increased over a 3-day period, while efflux occurred more rapidly within a 3-h time period. Four putative genes involved in Zn(2+) uptake and efflux in N. punctiforme were identified: (i) the predicted Co/Zn/Cd cation transporter, putative CDF; (ii) the predicted divalent heavy-metal cation transporter, putative Zip; (iii) the ATPase component and Fe/Zn uptake regulation protein, putative Fur; and (iv) an ABC-type Mn/Zn transport system, putative zinc ZnuC, ZnuABC system component. Quantitative real-time PCR indicated the responsiveness of all four genes to 22 microM ZnCl(2) within 3 h, followed by a reduction to below basal levels after 24 h by putative ZIP, ZnuC, and Fur and a reduction to below basal level after 72 h by putative CDF efflux gene. These results demonstrate differential regulation of zinc transporters over time, indicating a role for them in zinc homeostasis in N. punctiforme.
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