ArticlePlant physiology2009
A germin-like protein gene family functions as a complex quantitative trait locus conferring broad-spectrum disease resistance in rice.
Article in Plant physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.
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106 citing papers in PubMed, 261 citations in OpenAlex.
- Insights into lentil diversity, domestication, and the genetic basis of important agronomic traits through resequencing of 238 Lens accessions.The Plant journal : for cell and molecular biology · 2026Article
- CRISPR/Cas9-mediated mutagenesis of SMXL4 alters plant height and yield-related traits in rice (cv. Samkwang).Scientific reports · 2026Article
- Genome Identification ofPlants (Basel, Switzerland) · 2026Article
- Activation of OsOxO2 by T-DNA Insertion Affects Plant Height and Leaf Angle in Rice.Rice (New York, N.Y.) · 2026Article
- Genome-Wide Identification and Salinity Response Analysis of the Germin-like Protein (Plants (Basel, Switzerland) · 2025Article
- Transcriptomic analysis of rice cultivars with distinct resistance mechanisms toFrontiers in plant science · 2025Article
- Effect of Bacterial Extracellular Polymeric Substances fromMicroorganisms · 2024Article
- Defining genomic landscape for identification of potential candidate resistance genes associated with major rice diseases through MetaQTL analysis.Journal of biosciences · 2024Article
- Rice WRKY13 TF protein binds to motifs in the promoter region to regulate downstream disease resistance-related genes.Functional & integrative genomics · 2023Article
- iTRAQ based proteomic analysis of rice lines having single or stacked blast resistance genes:Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Molecular Characterization of Germin-like Protein Genes inACS omega · 2023Article
- Genome-wide analysis of the GLP gene family and overexpression of GLP1-5-1 to promote lignin accumulation during early somatic embryo development in Dimocarpus longan.BMC genomics · 2023Article
- OsGLP3-7 positively regulates rice immune response by activating hydrogen peroxide, jasmonic acid, and phytoalexin metabolic pathways.Molecular plant pathology · 2023Article
- Towards Marker-Assisted Breeding for Black Rot Bunch Resistance: Identification of a Major QTL in the Grapevine Cultivar 'Merzling'.International journal of molecular sciences · 2023Article
- The genome of Aechmea fasciata provides insights into the evolution of tank epiphytic habits and ethylene-induced flowering.Communications biology · 2022Article
- Genetic mapping and genomic prediction of sclerotinia stem rot resistance to rapeseed/canola (Brassica napus L.) at seedling stage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Meta-analysis reveals consensus genomic regions associated with multiple disease resistance in wheat (Molecular breeding : new strategies in plant improvement · 2022Article
- LIRBase: a comprehensive database of long inverted repeats in eukaryotic genomes.Nucleic acids research · 2022Article
- Genome-wide identification of germin-like proteins in peanut (Frontiers in plant science · 2022Article
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46 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant disease resistance governed by quantitative trait loci (QTL) is predicted to be effective against a broad spectrum of pathogens and long lasting. Use of these QTL to improve crop species, however, is hindered because the genes contributing to the trait are not known. Five disease resistance QTL that colocalized with defense response genes were accumulated by marker-aided selection to develop blast-resistant varieties. One advanced backcross line carrying the major-effect QTL on chromosome (chr) 8, which included a cluster of 12 germin-like protein (OsGLP) gene members, exhibited resistance to rice (Oryza sativa) blast disease over 14 cropping seasons. To determine if OsGLP members contribute to resistance and if the resistance was broad spectrum, a highly conserved portion of the OsGLP coding region was used as an RNA interference trigger to silence a few to all expressed chr 8 OsGLP family members. Challenge with two different fungal pathogens (causal agents of rice blast and sheath blight diseases) revealed that as more chr 8 OsGLP genes were suppressed, disease susceptibility of the plants increased. Of the 12 chr 8 OsGLPs, one clustered subfamily (OsGER4) contributed most to resistance. The similarities of sequence, gene organization, and roles in disease resistance of GLP family members in rice and other cereals, including barley (Hordeum vulgare) and wheat (Triticum aestivum), suggest that resistance contributed by the chr 8 OsGLP is a broad-spectrum, basal mechanism conserved among the Gramineae. Natural selection may have preserved a whole gene family to provide a stepwise, flexible defense response to pathogen invasion.
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