Evidence map›Paper›PMID 19009289›Full record

ArticleImmunogenetics2009

Non-coding RNAs revealed during identification of genes involved in chicken immune responses.

Marie-Laure Endale Ahanda, Thomas Ruby, Håkan Wittzell, Bertrand Bed'Hom, Anne-Marie Chaussé, Veronique Morin, Anne Oudin, Catherine Chevalier, John R Young, Rima Zoorob

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Immunogenetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Long non-coding RNAs (lncRNAs) and viral infections.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2013
    Article
  10. lncRNA expression signatures in response to enterovirus 71 infection.Biochemical and biophysical research communications · 2013
    Article
  11. Regulatory long non-coding RNA and its functions.Journal of physiology and biochemistry · 2012
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Marie-Laure Endale AhandaCNRS, FRE2937, 7 rue Guy Moquet, F-94800, Villejuif, France. endale@vjf.cnrs.fr
Thomas Ruby
Håkan Wittzell
Bertrand Bed'Hom
Anne-Marie Chaussé
Veronique Morin
Anne Oudin
Catherine Chevalier
John R Young
Rima Zoorob
Centre National de la Recherche Scientifique · FRAgroParisTech · FRInfectiologie Animale et Santé Publique · FRInserm · FRLund University · SEThe Pirbright Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent large-scale cDNA cloning studies have shown that a significant proportion of the transcripts expressed from vertebrate genomes do not appear to encode protein. Moreover, it was reported in mammals (human and mice) that these non-coding transcripts are expressed and regulated by mechanisms similar to those involved in the control of protein-coding genes. We have produced a collection of cDNA sequences from immunologically active tissues with the aim of discovering chicken genes involved in immune mechanisms, and we decided to explore the non-coding component of these immune-related libraries. After finding known non-coding RNAs (miRNA, snRNA, snoRNA), we identified new putative mRNA-like non-coding RNAs. We characterised their expression profiles in immune-related samples. Some of them showed changes in expression following viral infections. As they exhibit patterns of expression that parallel the behaviour of protein-coding RNAs in immune tissues, our study suggests that they could play an active role in the immune response.

Indexed as

AnimalsBirnaviridae InfectionsChickensDNA, ComplementaryExpressed Sequence TagsFemaleGene Expression ProfilingGene LibraryLymphocyte ActivationLymphoid TissueMaleMarek DiseaseMicroRNAsMolecular Sequence DataOligonucleotide Array Sequence AnalysisOrgan SpecificityDNA, ComplementaryMicroRNAsRNA, Untranslated

Identifiers

PMID19009289
OpenAlexW2011575027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.