Evidence map›Paper›PMID 19008252›Full record

ArticleBioinformatics (Oxford, England)2009

The SNPMaP package for R: a framework for genome-wide association using DNA pooling on microarrays.

Oliver S P Davis, Robert Plomin, Leonard C Schalkwyk

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Genetics of acute rejection after kidney transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Oliver S P DavisSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK. snpmap@iop.kcl.ac.uk
Robert Plomin
Leonard C Schalkwyk

Funding

Reading disability QTLs: pooled DNA on microarraysR01HD049861 · NICHD · KING'S COLLEGE LONDON · PI PLOMIN, ROBERT · 2006 to 2008
$794k
Medical Research Council G0500079Medical Research Council G0500079(73692)Medical Research Council G19/2Medical Research Council G9424799NICHD NIH HHS HD49861NICHD NIH HHS R01 HD049861Wellcome Trust 075492Wellcome Trust GR75492
6 · The paper itself

Abstract

summaryLarge-scale genome-wide association (GWA) studies using thousands of high-density SNP microarrays are becoming an essential tool in the search for loci related to heritable variation in many phenotypes. However, the cost of GWA remains beyond the reach of many researchers. Fortunately, the majority of statistical power can still be obtained by estimating allele frequencies from DNA pools, reducing the cost to that of tens, rather than thousands of arrays. We present a set of software tools for processing SNPMaP (SNP microarrays and pooling) data from CEL files to Relative Allele Scores in the rich R statistical computing environment.

Indexed as

Gene FrequencyPolymorphism, Single NucleotideSoftwareDNAGenomeGenome-Wide Association StudyOligonucleotide Array Sequence AnalysisDNA

Identifiers

PMID19008252
PMCPMC2639010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.