Evidence map›Paper›PMID 19007535›Full record

ReviewCurrent rheumatology reports2008

Churg-Strauss syndrome: 2005-2008 update.

Rafael G Grau

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 42 citations in OpenAlex.

  1. Churg-Straus syndrome: A case report.Iranian journal of neurology · 2017
    Article
  2. Article
  3. Article
  4. Skin involvement in ANCA-associated vasculitis.Clinical and experimental nephrology · 2013
    Review
  5. Article
  6. Article
  7. Review
  8. Asthma that is unresponsive to usual care.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2010
    Review
  9. Diagnosis and treatment of cerebral vasculitis.Therapeutic advances in neurological disorders · 2010
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rafael G GrauIndiana University School of Medicine, Division of Rheumatology, 1110 W. Michigan Street, LO-545, Indianapolis, IN 46202, USA. rgrau@iupui.edu
University School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Churg-Strauss syndrome (CSS) is a rare necrotizing small-vessel vasculitis associated with eosinophil-rich granulomatous inflammation of tissues and vessels and is also associated with asthma and eosinophilia. Epidemiologic studies continue to show that CSS is the rarest of the necrotizing small-vessel vasculitides. However, it is not possible to know with any certainty if there has been an increase in incidence. There has been an attempt to divide the patients with CSS into an antineutrophil cytoplasmic antibody-positive and cytoplasmic antibody-negative group. The former group has an increased frequency of renal involvement, parenchymal pulmonary disease, constitutional symptoms, and peripheral and central nervous system involvement, whereas the latter group has more frequent cardiac disease. The role of eosinophils and antineutrophil cytoplasmic antibodies remains poorly defined but provocative. Leukotriene receptor antagonists do not appear to induce CSS but facilitate the tapering of glucocorticoids, which unmasks the condition. Glucocorticoids and cyclophosphamide remain the foundation of treatment for vasculitis, but there are other promising and less toxic alternatives on the horizon.

Indexed as

Churg-Strauss SyndromeAntibodies, Antineutrophil CytoplasmicCyclophosphamideGlucocorticoidsHumansImmunosuppressive AgentsSurvival RateAntibodies, Antineutrophil CytoplasmicCyclophosphamideGlucocorticoidsImmunosuppressive Agents

Identifiers

PMID19007535
OpenAlexW2006832728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.