Evidence map›Paper›PMID 19005741›Full record

ReviewPharmaceutical research2009

Magnetothermally-responsive nanomaterials: combining magnetic nanostructures and thermally-sensitive polymers for triggered drug release.

Christopher S Brazel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmaceutical research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Role of Iron Oxide (FeNanomaterials (Basel, Switzerland) · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Clinical Trials of Thermosensitive Nanomaterials: An Overview.Nanomaterials (Basel, Switzerland) · 2019
    Review
  13. Review
  14. Article
  15. Article
  16. Magnetic Nanotransducers in Biomedicine.Chemistry (Weinheim an der Bergstrasse, Germany) · 2017
    Article
  17. Targeted Magnetic Nanotheranostics of Cancer.Molecules (Basel, Switzerland) · 2017
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Christopher S BrazelDepartment of Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, Alabama, 35487-0203, USA. cbrazel@eng.ua.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper reviews the design and development of magnetothermally-triggered drug delivery systems, whereby magnetic nanoparticles are combined with thermally-activated materials. By combining superparamagnetic nanoparticles with lower critical solution temperature (LCST) polymers, an alternating current (AC) magnetic field can be used to trigger localized heating in vivo, which in turn causes a phase change in the host polymer to allow diffusion and release of drugs. The use of magnetic nanoparticles for biomedical applications is reviewed, as well as the design of thermally-activated polymeric systems. Current research on externally-triggered delivery is highlighted, with a focus on the design and challenges in developing magnetothermally-activated systems.

Indexed as

MagneticsTemperatureAnimalsAntineoplastic AgentsChemical PhenomenaDrug CarriersDrug Delivery SystemsDrug DesignHumansMetal NanoparticlesNeoplasmsPolymersAntineoplastic AgentsDrug CarriersPolymers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.