Evidence map›Paper›PMID 19005338›Full record

ReviewCurrent opinion in pediatrics2008

American Academy of Pediatrics recommendations on the effects of early nutritional interventions on the development of atopic disease.

Ananth Thygarajan, Arvil W Burks

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 61 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Food allergen introduction patterns in the first year of life: A US nationwide survey.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
  5. Article
  6. [Epigenetic effects of human breastfeeding].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Early Life Eczema, Food Introduction, and Risk of Food Allergy in Children.Pediatric allergy, immunology, and pulmonology · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ananth ThygarajanDivision of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA. ananth.thyagarajan@duke.edu
Arvil W Burks
Duke University · USDuke University Hospital · US

Funding

RESEARCH TRAINING IN ALLERGY AND CLINICAL IMMUNOLOGYT32AI007062 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David B. Peden, John W. Sleasman · 1985 to 2026
$6.1M
NIAID NIH HHS T32 AI007062
6 · The paper itself

Abstract

purpose of reviewTo review the American Academy of Pediatrics statement on the effects of early nutritional interventions on the development of atopic disease in infants and children. RECENT

findingsRecent findings suggest that restriction of maternal diet during pregnancy and lactation does not play a major role in the development of allergic disease. In high-risk infants, exclusive breastfeeding for at least 4 months prevents or delays atopic dermatitis, cow milk allergy, and wheezing early in life. There is evidence that supplementing breastfeeding with a hydrolyzed formula protects against atopic disease, especially atopic dermatitis in at-risk infants. Finally, there is little evidence that delaying the introduction of complementary foods beyond 4-6 months of age has any protective effect against allergy. There is insufficient data that any dietary intervention beyond 4-6 months of age has any protective effect against developing atopic disease. SUMMARY: In high-risk infants, there is evidence that exclusive breastfeeding for at least 4 months, and delaying of complementary foods until 4-6 months, prevent the development of allergy. There is some evidence that supplementing hydrolyzed formulas in high-risk infants may delay or prevent allergic disease. There is no convincing evidence that maternal manipulation of diet during pregnancy or lactation, use of soy products, or infant dietary restrictions beyond 4-6 months has any effect on the development of atopic disease.

Indexed as

PediatricsPrenatal Nutritional Physiological PhenomenaSocieties, MedicalBreast FeedingFeeding BehaviorFemaleHumansHypersensitivity, ImmediateInfantInfant FoodInfant, NewbornInfant Nutritional Physiological PhenomenaPregnancyUnited States

Identifiers

PMID19005338
PMCPMC2659557
OpenAlexW2094015724

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.