ReviewJournal of biosciences2008
Astrocyte, the star avatar: redefined.
Review in Journal of biosciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 94 citations in OpenAlex.
- A highly efficient method to differentiate CGRP-expressing peptidergic nociceptors from human induced pluripotent stem cells.Stem cell reports · 2026Article
- HMC3 revealed: how much do these "Microglia" really tell us?Frontiers in immunology · 2026Review
- Understanding crosstalk of organ tropism, tumor microenvironment and noncoding RNAs in breast cancer metastasis.Molecular biology reports · 2023Review
- Skin Wound following Irradiation Aggravates Radiation-Induced Brain Injury in a Mouse Model.International journal of molecular sciences · 2023Article
- Neurons and Glia Interplay in α-Synucleinopathies.International journal of molecular sciences · 2021Review
- Investigating the Convergent Mechanisms between Major Depressive Disorder and Parkinson's Disease.Complex psychiatry · 2021Review
- Review
- A Review and Hypothesized Model of the Mechanisms That Underpin the Relationship Between Inflammation and Cognition in the Elderly.Frontiers in aging neuroscience · 2019Article
- Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen‑glucose deprivation.Molecular medicine reports · 2018Article
- Breast cancer brain metastasis: molecular mechanisms and directions for treatment.Neuro-oncology · 2018Review
- Astrocyte-specific overexpressed gene signatures in response to methamphetamine exposure in vitro.Journal of neuroinflammation · 2017Article
- Astrocyte Apoptosis and HIV Replication Are Modulated in Host Cells Coinfected withFrontiers in cellular and infection microbiology · 2017Article
- Adenosine kinase facilitated astrogliosis-induced cortical neuronal death in traumatic brain injury.Journal of molecular histology · 2016Article
- Reactivated astrocytes as a possible source of oligodendrocyte precursors for remyelination in remitting phase of experimental autoimmune encephalomyelitis rats.American journal of translational research · 2016Article
- Article
- Pathophysiogenesis of mesial temporal lobe epilepsy: is prevention of damage antiepileptogenic?Current medicinal chemistry · 2014Review
- The role of EGFR and ErbB family related proteins in the oligodendrocyte specification in germinal niches of the adult mammalian brain.Frontiers in cellular neuroscience · 2013Review
- A human astrocytoma cell line is highly susceptible to infection with Trypanosoma cruzi.Memorias do Instituto Oswaldo Cruz · 2013Article
- Depression and treatment response: dynamic interplay of signaling pathways and altered neural processes.Cellular and molecular life sciences : CMLS · 2013Review
- The effects of trypsin on rat brain astrocyte activation.Iranian journal of neurology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Until recently, the neuroscience community held the belief that glial cells such as astrocytes and oligodendrocytes functioned solely as "support" cells of the brain. In this role, glial cells simply provide physical support and housekeeping functions for the more important cells of the brain, the neurons. However, this view has changed radically in recent years with the discovery of previously unrecognized and surprising functions for this underappreciated cell type. In the past decade or so, emerging evidence has provided new insights into novel glial cell activities such as control of synapse formation and function, communication,cerebrovascular tone regulation, immune regulation and adult neurogenesis. Such advances in knowledge have effectively elevated the role of the astrocyte to one that is more important than previously realized. This review summarizes the past and present knowledge of glial cell functions that has evolved over the years, and has resulted in a new appreciation of astrocytes and their value in studying the neurobiology of human brain cells and their functions. In this review, we highlight recent advances in the role of glial cells in physiology, pathophysiology and, most importantly, in adult neurogenesis and "stemness", with special emphasis on astrocytes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.