Evidence map›Paper›PMID 19005036›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2008

Epigenetics in the nervous system.

Yan Jiang, Brett Langley, Farah D Lubin, William Renthal, Marcelo A Wood, Dag H Yasui, Arvind Kumar, Eric J Nestler, Schahram Akbarian, Andrea C Beckel-Mitchener

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Epigenetic modification in Parkinson's disease.Frontiers in cell and developmental biology · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. DNA Methylation and Non-Coding RNAs during Tissue-Injury Associated Pain.International journal of molecular sciences · 2022
    Review
  13. A Neuroscience Primer for Integrating Geroscience With the Neurobiology of Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  14. Review
  15. Review
  16. Epigenetic Age Acceleration and Cognitive Decline: A Twin Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  17. Histone Methylation Regulation in Neurodegenerative Disorders.International journal of molecular sciences · 2021
    Review
  18. Review
  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan JiangBrudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts 01604, USA.
Brett Langley
Farah D Lubin
William Renthal
Marcelo A Wood
Dag H Yasui
Arvind Kumar
Eric J Nestler
Schahram Akbarian
Andrea C Beckel-Mitchener

Funding

MOLECULAR STUDIES OF COCAINE ACTION IN BRAINR37DA007359 · NIDA · YALE UNIVERSITY · PI NESTLER, ERIC J. · 1996 to 2020
$6.9M
Basic Science Training Program in Drug Abuse ResearchT32DA007290 · NIDA · YALE UNIVERSITY · PI SELF, DAVID W · 1992 to 2017
$6.7M
The Role of MeCP2 in Rett SyndromeR01HD041462 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LASALLE, JANINE M · 2002 to 2011
$2.8M
Remodeling Neuronal Chromatin in Mouse Models for DepressionR01MH086509 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI AKBARIAN, SCHAHRAM · 2010 to 2014
$2.0M
Chromatin Remodeling and Memory StorageR01MH081004 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI WOOD, MARCELO ANDRES · 2008 to 2012
$1.9M
Epigenetic Etiologies of Autism-Spectrum DisordersR01HD048799 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LASALLE, JANINE M · 2005 to 2009
$1.8M
iCys Laser Scanning Cytometer for UC Davis CoreS10RR024747 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LASALLE, JANINE M · 2008 to 2008
$500k
Treating Depression with Histone Deacetylase InhibitorsR01MH074114 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI AKBARIAN, SCHAHRAM · 2005 to 2006
$476k
Epigenetic Mechanisms of Gene Regulation in Long-Term Memory FormationK99MH082106 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUBIN, FARAH DOMINIQUE · 2008 to 2008
$84k
NCRR NIH HHS S10 RR024747NICHD NIH HHS R01 HD041462NICHD NIH HHS R01 HD048799NIDA NIH HHS R37 DA007359NIDA NIH HHS T32 DA007290NIMH NIH HHS K99 MH082106NIMH NIH HHS R01 MH074114NIMH NIH HHS R01 MH081004NIMH NIH HHS R01 MH086509
6 · The paper itself

Abstract

It is becoming increasingly clear that epigenetic modifications are critical factors in the regulation of gene expression. With regard to the nervous system, epigenetic alterations play a role in a diverse set of processes and have been implicated in a variety of disorders. Gaining a more complete understanding of the essential components and underlying mechanisms involved in epigenetic regulation could lead to novel treatments for a number of neurological and psychiatric conditions.

Indexed as

AnimalsBrain DiseasesChromatinDNA MethylationEpigenesis, GeneticGene Expression RegulationGenetic Predisposition to DiseaseHistone Deacetylase InhibitorsHistone DeacetylasesHistonesHumansNervous SystemChromatinHistone Deacetylase InhibitorsHistone DeacetylasesHistones

Identifiers

PMID19005036
PMCPMC3844836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.