Evidence map›Paper›PMID 19003489›Full record

ArticleCognitive neurodynamics2008

An empirical EEG analysis in brain death diagnosis for adults.

Zhe Chen, Jianting Cao, Yang Cao, Yue Zhang, Fanji Gu, Guoxian Zhu, Zhen Hong, Bin Wang, Andrzej Cichocki

Abstract read
In one paragraph

Article in Cognitive neurodynamics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  5. Article
  6. Article
  7. Article
  8. Analyzing EEG of quasi-brain-death based on dynamic sample entropy measures.Computational and mathematical methods in medicine · 2013
    Article
  9. Article
  10. Article
  11. Article
  12. New mechanics of traumatic brain injury.Cognitive neurodynamics · 2009
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhe ChenLaboratory for Advanced Brain Signal Processing, RIKEN Brain Science Institute, Wako-shi, Saitama, 351-0198, Japan, zhechen@neurostat.mgh.harvard.edu.
Jianting Cao
Yang Cao
Yue Zhang
Fanji Gu
Guoxian Zhu
Zhen Hong
Bin Wang
Andrzej Cichocki

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electroencephalogram (EEG) is often used in the confirmatory test for brain death diagnosis in clinical practice. Because EEG recording and monitoring is relatively safe for the patients in deep coma, it is believed to be valuable for either reducing the risk of brain death diagnosis (while comparing other tests such as the apnea) or preventing mistaken diagnosis. The objective of this paper is to study several statistical methods for quantitative EEG analysis in order to help bedside or ambulatory monitoring or diagnosis. We apply signal processing and quantitative statistical analysis for the EEG recordings of 32 adult patients. For EEG signal processing, independent component analysis (ICA) was applied to separate the independent source components, followed by Fourier and time-frequency analysis. For quantitative EEG analysis, we apply several statistical complexity measures to the EEG signals and evaluate the differences between two groups of patients: the subjects in deep coma, and the subjects who were categorized as brain death. We report statistically significant differences of quantitative statistics with real-life EEG recordings in such a clinical study, and we also present interpretation and discussions on the preliminary experimental results.

Identifiers

PMID19003489
PMCPMC2518749

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.