ArticleCytotechnology1999
Effects of green, oolong and black teas and related components on the proliferation and invasion of hepatoma cells in culture.
Article in Cytotechnology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Oolong tea consumption and its interactions with a novel composite index on esophageal squamous cell carcinoma.BMC complementary and alternative medicine · 2019Article
- Tea and Its Components Prevent Cancer: A Review of the Redox-Related Mechanism.International journal of molecular sciences · 2019Review
- Article
- Induction of apoptosis with mitochondrial membrane depolarization by a glycyrrhetinic acid derivative in human leukemia K562 cells.Cytotechnology · 2012Article
- Anti-cancer activities of tea epigallocatechin-3-gallate in breast cancer patients under radiotherapy.Current molecular medicine · 2012Article
- Antiproliferative and anti-invasive effect of piceatannol, a polyphenol present in grapes and wine, against hepatoma AH109A cells.Journal of biomedicine & biotechnology · 2012Article
- Plant phenolics: extraction, analysis and their antioxidant and anticancer properties.Molecules (Basel, Switzerland) · 2010Review
- Suppression of human lung cancer cell growth and migration by berbamine.Cytotechnology · 2010Article
- Inhibitory effects of norcantharidin against human lung cancer cell growth and migration.Cytotechnology · 2010Article
- Suppression of growth of highly-metastatic human breast cancer cells by norcantharidin and its mechanisms of action.Cytotechnology · 2009Article
- Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells.Cytotechnology · 2009Article
- Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling.Cytotechnology · 2009Article
- Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration.Cytotechnology · 2009Article
- Inhibition of invasion and up-regulation of E-cadherin expression in human malignant melanoma cell line A375 by (-)-epigallocatechin-3-gallate.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2008Article
- Inhibitory effects of theanine and sera from theanine-fed rats on receptor-mediated cancer cell invasion beneath mesothelial-cell monolayers.Cytotechnology · 2001Article
- Inhibition of hepatoma cell invasion beneath mesothelial-cell monolayer by sera from tea- and related component-treated rats and their modes of action.Cytotechnology · 2001Article
- Inhibitory effect of curcumin on the invasion of rat ascites hepatoma cells in vitro and ex vivo.Cytotechnology · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of teas and related components on the proliferation and invasion of cancer cells were examined by employing both in vitro proliferation and invasion assay systems. Powdered green, oolong and black tea extracts dose-dependently inhibited proliferation and invasion of a rat ascites hepatoma cell line of AH109A but did not affect the proliferation of the normal mesentery-derived mesothelial cells (M-cells) isolated from rats; higher concentrations of powdered oolong and black teas could restrain the proliferation of another tumor cell line of L929. The AH109A cells were found to penetrate underneath the monolayer of M-cells in the presence of 10% calf serum. When each rat serum obtained at 0.5, 1, 2, 3 and 5 h after oral intubation of each tea extract was added to the culture media instead of calf serum at a concentration of 10%, both the invasion and proliferation of AH109A were significantly suppressed. These ex vivo results suggest the potential bioavailability of effective tea components in rats. Furthermore, (-)-epigallocatechin gallate, (-)-epicatechin gallate and (-)-epigallocatechin from green tea as well as the mixture of theaflavin and theaflavin gallates from black tea were shown to be the most effective components against the invasion and proliferation of AH109A. These results show that the inhibitory effects of the teas and related components against AH109A cells are due to the cell-specific and higher sensitivity of the cell line to tea components.
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Registered trials
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