Evidence map›Paper›PMID 19002744›Full record

ReviewCerebellum (London, England)2008

Development of cerebellar GABAergic interneurons: origin and shaping of the "minibrain" local connections.

Ketty Leto, Alice Bartolini, Ferdinando Rossi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cerebellum (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Mapping the developmental profile of ventricular zone-derived neurons in the human cerebellum.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  8. Cellular commitment in the developing cerebellum.Frontiers in cellular neuroscience · 2014
    Review
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  15. Laminar fate and phenotype specification of cerebellar GABAergic interneurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ketty LetoDepartment of Neuroscience and Rita Levi Montalcini Centre for Brain Repair, National Institute of Neuroscience, University of Turin, Turin, Italy. ketty.leto@unito.it
Alice Bartolini
Ferdinando Rossi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cerebellar circuits comprise a limited number of neuronal phenotypes embedded in a defined cytoarchitecture and generated according to specific spatio-temporal patterns. The local GABAergic network is composed of several interneuron phenotypes that play essential roles in information processing by modulating the activity of cerebellar cortical inputs and outputs. A major issue in the study of cerebellar development is to understand the mechanisms that underlie the generation of different interneuron classes and regulate their placement in the cerebellar architecture and integration in the cortico-nuclear network. Recent findings indicate that the variety of cerebellar interneurons derives from a single population of multipotent progenitors whose fate choices are determined by instructive environmental information. Such a strategy, which is unique for the cerebellum along the neuraxis, allows great flexibility in the control of the quality and quantity of GABAergic interneurons that are produced, thus facilitating the adaptive shaping of the cerebellar network to specific functional demands.

Indexed as

AnimalsBrainCell DifferentiationCerebellar CortexCerebellumgamma-Aminobutyric AcidGlutamic AcidInterneuronsModels, NeurologicalNerve Tissue ProteinsPrimatesRodentiaStem Cellsgamma-Aminobutyric AcidGlutamic AcidNerve Tissue Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.