ArticleCell stress & chaperones2009
Transcriptional expression levels of cell stress marker genes in the Pacific oyster Crassostrea gigas exposed to acute thermal stress.
Article in Cell stress & chaperones, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 103 citations in OpenAlex.
- Short-term impacts of embryonic thermal manipulation in mule duck, a kinetic study: new tools for metabolic programming.BMC genomics · 2025Article
- Transcriptome-To-Phenome Response of Larval Eastern Oysters Under Multiple Drivers of Aragonite Undersaturation.Ecology and evolution · 2025Article
- Article
- Transient Receptor Potential (TRP) Channels in the Pacific Oyster (International journal of molecular sciences · 2021Article
- Post-ejaculation thermal stress causes changes to the RNA profile of sperm in an external fertilizer.Proceedings. Biological sciences · 2020Article
- Transcriptional Alteration of Gene Biomarkers in Hemocytes of WildPathogens (Basel, Switzerland) · 2020Article
- Impact of Ocean Acidification on the Energy Metabolism and Antioxidant Responses of the Yesso Scallop (Frontiers in physiology · 2018Article
- Differential response to stress inPeerJ · 2018Article
- Contrasting impacts of ocean acidification and warming on the molecular responses of COBMC genomics · 2017Article
- The novel transcriptional factor HP1BP3 negatively regulates Hsp70 transcription in Crassostrea hongkongensis.Scientific reports · 2017Article
- Expression Characterization of Stress Genes Under High and Low Temperature Stresses in the Pacific Oyster, Crassostrea gigas.Marine biotechnology (New York, N.Y.) · 2016Article
- Effects of Antifouling Biocides on Molecular and Biochemical Defense System in the Gill of the Pacific Oyster Crassostrea gigas.PloS one · 2016Article
- Anticipatory gene regulation driven by maternal effects in an insect-host system.Ecology and evolution · 2015Article
- qRT-PCR evaluation of the transcriptional response of zebra mussel to heavy metals.BMC genomics · 2015Article
- Article
- Article
- Genome and transcriptome analyses provide insight into the euryhaline adaptation mechanism of Crassostrea gigas.PloS one · 2013Article
- Effects of heavy metals on the expression of a zinc-inducible metallothionein-III gene and antioxidant enzyme activities in Crassostrea gigas.Ecotoxicology (London, England) · 2012Article
- Cellular and transcriptional responses of Crassostrea gigas hemocytes exposed in vitro to brevetoxin (PbTx-2).Marine drugs · 2012Article
- Network analysis of oyster transcriptome revealed a cascade of cellular responses during recovery after heat shock.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the annual cycle, oysters are exposed to seasonal slow changes in temperature, but during emersion at low tide on sunny summer days, their internal temperature may rise rapidly, resulting in acute heat stress. We experimentally exposed oysters to a 1-h acute thermal stress and investigated the transcriptional expression level of some genes involved in cell stress defence mechanisms, including chaperone proteins (heat shock proteins Hsp70, Hsp72 and Hsp90 (HSP)), regulation of oxidative stress (Cu-Zn superoxide dismutase, metallothionein (MT)), cell detoxification (glutathione S-transferase sigma, cytochrome P450 and multidrug resistance (MDR1)) and regulation of the cell cycle (p53). Gene mRNA levels were quantified by reverse transcription-quantitative polymerase chain reaction and expressed as their ratio to actin mRNA, used as a reference. Of the nine genes studied, HSP, MT and MDR1 mRNA levels increased in response to thermal stress. We compared the responses of oysters exposed to acute heat shock in summer and winter and observed differences in terms of magnitude and kinetics. A larger increase was observed in September, with recovery within 48 h, whereas in March, the increase was smaller and lasted more than 2 days. The results were also compared with data obtained from the natural environment. Though the functional molecule is the protein and information at the mRNA level only has limitations, the potential use of mRNAs coding for cell stress defence proteins as early sensitive biomarkers is discussed.
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