Trial reportClinical orthopaedics and related research2009
Two-stage cementless revision of infected hip endoprostheses.
Trial report in Clinical orthopaedics and related research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Mechanical complications of hip spacers: a systematic review of the literature.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Does cemented or cementless single-stage exchange arthroplasty of chronic periprosthetic hip infections provide similar infection rates to a two-stage? A systematic review.BMC infectious diseases · 2016Pooled it
- Infection in total hip replacement: meta-analysis.International orthopaedics · 2011Pooled it
- Septic Two-Stage Cementless Hip Revision Arthroplasty Is Safe but Has Higher Complication and Mortality Rates in Older Adults.Journal of clinical medicine · 2025Article
- Early Administration of Rifampicin Does Not Induce Increased Resistance in Septic Two-Stage Revision Knee and Hip Arthroplasty.Antibiotics (Basel, Switzerland) · 2025Article
- 'Hybrid' spacers in two-stage total hip arthroplasty revision: surgical technique, clinical and radiographic outcomes.Archives of orthopaedic and trauma surgery · 2025Article
- Predictive Factors for Risk of Reinfection in Septic Two-Stage Revision of Total Hip and Knee Arthroplasties.Antibiotics (Basel, Switzerland) · 2025Article
- Impact of Manual Addition of Vancomycin to Polymethylmethacrylate (PMMA) Cements.Antibiotics (Basel, Switzerland) · 2024Article
- Effect of Multiantibiotic-Loaded Bone Cement on the Treatment of Periprosthetic Joint Infections of Hip and Knee Arthroplasties-A Single-Center Retrospective Study.Antibiotics (Basel, Switzerland) · 2024Article
- Clinical evaluation of a new technique for custom-made spacers in septic two-stage revision of total hip arthroplasties.Archives of orthopaedic and trauma surgery · 2023Article
- Risk factors of reinfection after prosthesis removal and antibiotic bone cement spacer implantation for the treatment of periprosthetic joint infection.BMC infectious diseases · 2022Article
- A review of current practices in periprosthetic joint infection debridement and revision arthroplasty.Arthroplasty (London, England) · 2022Review
- Diagnostic Value of CRP and Serum WBC Count during Septic Two-Stage Revision of Total Hip Arthroplasties.Antibiotics (Basel, Switzerland) · 2022Article
- New Technique for Custom-Made Spacers in Septic Two-Stage Revision of Total Hip Arthroplasties.Antibiotics (Basel, Switzerland) · 2021Article
- Successful Two-Stage Exchange Arthroplasty for Periprosthetic Infection Following Total Knee Arthroplasty: The Impact of Timing on Eradication of Infection.International journal of medical sciences · 2021Article
- Radial Extracorporeal Shock Wave Therapy AgainstMicroorganisms · 2020Article
- Comparison of efficacy and complications between two types of staging arthroplasty in treating chronic septic hip arthritis: A retrospective clinical study.Experimental and therapeutic medicine · 2019Article
- High cure rate of periprosthetic hip joint infection with multidisciplinary team approach using standardized two-stage exchange.Journal of orthopaedic surgery and research · 2019Observational
- Single-stage Acetabular Revision During Two-stage THA Revision for Infection is Effective in Selected Patients.Clinical orthopaedics and related research · 2017Article
- Antibacterial Effect of a 4x Cu-TiO₂ Coating Simulating Acute Periprosthetic Infection-An Animal Model.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledCementless two-stage revision of infected total hip prostheses lacks the possibility of local antibiotic protection of the implant at the time of reimplantation, which leads to the concern that this protocol may not sufficiently eradicate periprosthetic infection. Moreover, early implant loosening as much as 18% and stem subsidence as much as 30% have been reported. To determine whether a cementless revision could eradicate infection and achieve sufficient implant stability, we prospectively followed 36 patients with two-stage revisions for septic hip prostheses. We used a uniform protocol of a 6-week spacer interval, specific local and systemic antibiotic therapies, and cementless modular revision stems. The minimum followup was 24 months (mean, 35 months; range, 24-60 months). In one patient, the spacer was changed when the C-reactive protein value failed to normalize after 6 weeks, and the reimplantation was performed after an additional 6 weeks. No infections recurred. There was no implant loosening and a 94% bone-ingrowth fixation of stems. Subsidence occurred in two patients. The Harris hip score increased from a preoperative mean of 41 to 90 at 12 months after reimplantation and later. Using cementless prostheses in two-stage revisions of periprosthetic infections of the hip in combination with a specific local and systemic antibiotic therapy seems to eradicate infection and provide implant stability. LEVEL OF EVIDENCE: Level IV, therapeutic study.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.