ArticleApplied optics2008
Measuring mucosal blood supply in vivo with a polarization-gating probe.
Article in Applied optics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- Assessment of tissue pathology using optical polarimetry.Lasers in medical science · 2022Article
- Isolating individual polarization effects from the Mueller matrix: comparison of two non-decomposition techniques.Biomedical optics express · 2021Article
- Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer.BMC cancer · 2018Article
- Fully automated fiber-based optical spectroscopy system for use in a clinical setting.Journal of biomedical optics · 2018Article
- Flexible polarimetric probe for 3 × 3 Mueller matrix measurements of biological tissue.Scientific reports · 2017Article
- Detection of precancerous lesions in the oral cavity using oblique polarized reflectance spectroscopy: a clinical feasibility study.Journal of biomedical optics · 2017Article
- Rectal Optical Markers for In Vivo Risk Stratification of Premalignant Colorectal Lesions.Clinical cancer research : an official journal of the American Association for Cancer Research · 2015Article
- In vivo risk analysis of pancreatic cancer through optical characterization of duodenal mucosa.Pancreas · 2015Article
- Polarization gating spectroscopy of normal-appearing duodenal mucosa to detect pancreatic cancer.Gastrointestinal endoscopy · 2014Article
- Algorithm for automated selection of application-specific fiber-optic reflectance probes.Journal of biomedical optics · 2013Article
- Advances in biophotonics detection of field carcinogenesis for colon cancer risk stratification.Journal of Cancer · 2013Article
- Method of detecting tissue contact for fiber-optic probes to automate data acquisition without hardware modification.Biomedical optics express · 2013Article
- Perturbation Monte Carlo methods for tissue structure alterations.Biomedical optics express · 2013Article
- Analytical light reflectance models for overlapping illumination and collection area geometries.Applied optics · 2012Article
- Monte Carlo model of the penetration depth for polarization gating spectroscopy: influence of illumination-collection geometry and sample optical properties.Applied optics · 2012Article
- In vivo measurement of the shape of the tissue-refractive-index correlation function and its application to detection of colorectal field carcinogenesis.Journal of biomedical optics · 2012Article
- Multiple scattering model for the penetration depth of low-coherence enhanced backscattering.Journal of biomedical optics · 2011Article
- Measurement of optical scattering properties with low-coherence enhanced backscattering spectroscopy.Journal of biomedical optics · 2011Article
- Depth-selective fiber-optic probe for characterization of superficial tissue at a constant physical depth.Biomedical optics express · 2011Article
- Light-scattering technologies for field carcinogenesis detection: a modality for endoscopic prescreening.Gastroenterology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
There has been significant interest in developing depth-selective optical interrogation of biological tissue in general and of superficial (e.g., mucosal) tissue in particular. We report an in vivo polarization-gating fiber-optic probe that obtains backscattering spectroscopic measurements from a range of near-surface depths (100-200 microm). The design and testing was performed with polarized light Monte Carlo simulations and in tissue model experiments. We used the probe to investigate mucosal changes in early carcinogenesis. Measurements performed in the colonic mucosa of 125 human subjects provide the first in vivo evidence that mucosal blood supply is increased early in carcinogenesis, not only in precancerous adenomatous lesions, but also in the histologically normal-appearing tissue surrounding these lesions. This effect was primarily limited to the mucosal microcirculation and was not present in the larger blood vessels located deeper in colonic tissue.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.