ReviewCell cycle (Georgetown, Tex.)2008
Function of cyclins in regulating the mitotic and meiotic cell cycles in male germ cells.
Review in Cell cycle (Georgetown, Tex.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Functional Analysis of the Cyclin E Gene in the Reproductive Development of Rainbow Trout (Biology · 2025Article
- Genes as Genome Stabilizers in Pluripotent Stem Cells.Advances in experimental medicine and biology · 2025Review
- Potential Immunohistochemical Biomarkers for Grading Oral Dysplasia: A Literature Review.Biomedicines · 2024Review
- Biallelic variant in cyclin B3 is associated with failure of maternal meiosis II and recurrent digynic triploidy.Journal of medical genetics · 2021Article
- Nuclear translocation of MTL5 from cytoplasm requires its direct interaction with LIN9 and is essential for male meiosis and fertility.PLoS genetics · 2021Article
- Genome-wide DNA methylation dynamics during epigenetic reprogramming in the porcine germline.Clinical epigenetics · 2021Article
- TP53 mediated miR-3647-5p prevents progression of cervical carcinoma by targeting AGR2.Cancer medicine · 2019Article
- Article
- Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model.Cell journal · 2017Article
- Characterizing the Spermatogonial Response to Retinoic Acid During the Onset of Spermatogenesis and Following Synchronization in the Neonatal Mouse Testis.Biology of reproduction · 2016Article
- Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis.PLoS genetics · 2014Article
- Role of cyclins in controlling progression of mammalian spermatogenesis.The International journal of developmental biology · 2013Review
- Methanol may function as a cross-kingdom signal.PloS one · 2012Article
- MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets.PloS one · 2011Article
- The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse.PloS one · 2010Article
- Global microRNA characterization reveals that miR-103 is involved in IGF-1 stimulated mouse intestinal cell proliferation.PloS one · 2010Article
- Tight junctions in the testis: new perspectives.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010Review
- Expression of cell cycle-related genes with cytokine-induced cell cycle progression of primitive hematopoietic stem cells.Stem cells and development · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The specialized cell cycles that characterize various aspects of the differentiation of germ cells provide a unique opportunity to understand heretofore elusive aspects of the in vivo function of cell cycle regulators. Key components of the cell cycle machinery are the regulatory sub-units, the cyclins, and their catalytic partners, the cyclin-dependent kinases. Some of the cyclins exhibit unique patterns of expression in germ cells that suggest possible concomitant distinct functions, predictions that are being explored by targeted mutagenesis in mouse models. A novel, meiosis-specific function has been shown for one of the A-type cyclins, cyclin A1. Embryonic lethality has obviated understanding of the germline functions of cyclin A2 and cyclin B1, while yet other cyclins, although expressed at specific stages of germ cell development, may have less essential function in the male germline.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.