Evidence map›Paper›PMID 19001605›Full record

ArticleJournal of the National Cancer Institute2008

Recent trends in breast cancer among younger women in the United States.

Louise A Brinton, Mark E Sherman, J Daniel Carreon, William F Anderson

2 registry-linked trialsAbstract readComparative Study
In one paragraph

Article in Journal of the National Cancer Institute, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 115 papers.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01734499 nacompletednot on this mapstarted 2012, after this paper: background citation

The Change Cycle Intervention for Improving Quality of Life in Breast Cancer Survivors

TypeinterventionalSponsorTexas Tech University Health Sciences CenterRan2012 to 2015Enrolled120ConditionsBreast CancerArmsCoping Class, Standard of Care, FACT-B Quality of Life
NCT02308085 naactive not recruitingnot on this mapstarted 2014, after this paper: background citation

A Study Evaluating the Pregnancy Outcomes and Safety of Interrupting Endocrine Therapy for Young Women With Endocrine Responsive Breast Cancer Who Desire Pregnancy

TypeinterventionalSponsorETOP IBCSG Partners FoundationRan2014 to 2028Enrolled518ConditionsEarly Breast CancerArmsEndocrine therapy interruption
3 · Its place in the literature

Who cites it

115 citing papers in PubMed.

  1. Trial
  2. Article
  3. Breast Cancer Polygenic Risk Score Associated with Outcomes after In Situ Breast Disease.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. The necessity of adjuvant chemotherapy in young patients with TClinical and experimental medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Does age affect outcome with breast cancer?Breast (Edinburgh, Scotland) · 2023
    Article
  15. Article
  16. Article
  17. Breastfeeding and the patient's perspective.Abdominal radiology (New York) · 2023
    Review
  18. Article
  19. Article
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Louise A BrintonDivision of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, Bethesda, MD 20852-7234, USA. brinton@nih.gov
Mark E Sherman
J Daniel Carreon
William F Anderson

Funding

Intramural NIH HHS
6 · The paper itself

Abstract

Increases in the incidence of postmenopausal breast cancers have been linked to screening and menopausal hormone use, but younger women have received less attention. Thus, we analyzed trends in breast cancer incidence (N = 387 231) using the National Cancer Institute's Surveillance, Epidemiology, and End Results Program 13-Registry database (1992-2004). Whites had higher incidence rates than blacks after age 40 years, but the reverse was true among younger women (black-white crossover). Among younger women, the rate per 100,000 woman-years was 16.8 for black vs 15.1 for white women; the highest black-white incidence rate ratio (IRR) was seen among women younger than 30 years (IRR = 1.52, 95% confidence interval = 1.34 to 1.73). This risk pattern was not observed in other ethnic groups. The black-white crossover among younger women was largely restricted to breast cancers with favorable tumor characteristics. The annual percentage change in the incidence of invasive breast cancers decreased modestly among older women but increased among younger (<40 years) white women. Continued surveillance of trends is needed, particularly for molecular subtypes that preferentially occur among young women.

Indexed as

PremenopauseAdultAge DistributionAge FactorsBiomarkers, TumorBlack or African AmericanBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularConfounding Factors, EpidemiologicFemaleHispanic or LatinoHumansIncidenceLymphatic MetastasisBiomarkers, TumorReceptors, EstrogenReceptors, Progesterone

Identifiers

PMID19001605
PMCPMC2720764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.