ArticleGenetics2009
Ancient trans-specific polymorphism at pheromone receptor genes in basidiomycetes.
Article in Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 77 citations in OpenAlex.
- EASYstrata: an all-in-one workflow for genome annotation and genomic divergence analysis.NAR genomics and bioinformatics · 2025Article
- Repeated loss of function at HD mating-type genes and of recombination in anther-smut fungi.Nature communications · 2025Article
- The Evolution of Extreme Genetic Variability in a Parasite-Resistance Complex.Genome biology and evolution · 2024Article
- Genome biology and evolution of mating-type loci in four cereal rust fungi.PLoS genetics · 2024Article
- Frequent transitions in mating-type locus chromosomal organization inProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Frequent transitions in mating-type locus chromosomal organization inbioRxiv : the preprint server for biology · 2023Article
- Onset and stepwise extensions of recombination suppression are common in mating-type chromosomes of Microbotryum anther-smut fungi.Journal of evolutionary biology · 2022Article
- Ontogenetic Variation in Macrocyclic and Hemicyclic Poplar Rust Fungi.International journal of molecular sciences · 2022Article
- Article
- Large-scale fungal strain sequencing unravels the molecular diversity in mating loci maintained by long-term balancing selection.PLoS genetics · 2022Article
- Trans-specific polymorphism and the convergent evolution of supertypes in major histocompatibility complex class II genes in darters (Ecology and evolution · 2022Article
- Identification of the sex-determining factor in the liverwort Marchantia polymorpha reveals unique evolution of sex chromosomes in a haploid system.Current biology : CB · 2021Article
- Evolutionary Genomics of Sex-Related Chromosomes at the Base of the Green Lineage.Genome biology and evolution · 2021Article
- Article
- Recombination suppression and evolutionary strata around mating-type loci in fungi: documenting patterns and understanding evolutionary and mechanistic causes.The New phytologist · 2021Review
- The Untapped Australasian Diversity of Astaxanthin-Producing Yeasts with Biotechnological Potential-Microorganisms · 2020Article
- The smut fungi of Greenland.MycoKeys · 2020Article
- Article
- Convergent recombination cessation between mating-type genes and centromeres in selfing anther-smut fungi.Genome research · 2019Article
- Evolutionary strata on young mating-type chromosomes despite the lack of sexual antagonism.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the majority of sexual organisms, reproduction occurs almost exclusively through the combination of distinct and alternate forms, called sexes or mating types. In some fungi, there can be dozens to hundreds of alternate alleles that determine compatible mating types. Such extensive polymorphism is expected to be maintained by balancing selection, and in extreme cases may give rise to trans-specific polymorphism. Here, we analyzed sequences of two pheromone receptors in the Microbotryum fungal species complex (Basidiomycota), which has only two alternate mating types. Several lines of evidence strongly suggest that the pheromone receptors are two allelic sequences acting to determine the alternate A1 and A2 mating types required for mating in Microbotryum. Phylogenetic trees of pheromone receptors in the Microbotryum species complex indicated a trans-specific polymorphism: the Microbotryum sequences from a given mating type were all more similar to the pheromone receptors of distantly related classes of fungi than to the alternate pheromone receptor in the Microbotryum species. A phylogenetic tree built using other known pheromone receptors from basidiomycetes showed that trans-specific polymorphism is widespread. The pheromone receptor alleles from Microbotryum appeared as the oldest, being at least 370 million years old. This represents the oldest known trans-specific polymorphism known in any organism so far, which may be due to the existence of sex chromosomes, obligate sexuality, mitochondrial inheritance linked to the mating type, and a highly selfing mating system in Microbotryum.
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