Trial reportAmerican journal of preventive medicine2008
Computerized counseling for folate knowledge and use: a randomized controlled trial.
Trial report in American journal of preventive medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00177515 (Preventive Health Education for Women of Reproductive Age), which is not on this map. Cited by 18 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preventive Health Education for Women of Reproductive Age
Who cites it
18 citing papers in PubMed, 6 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Behavior changes to promote preconception health: a systematic review.BMC women's health · 2025Pooled it
- Preconception, Interconception, and reproductive health screening tools: A systematic review.Health services research · 2023Pooled it
- Effectiveness of preconception interventions in primary care: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022Pooled it
- Preconception health interventions delivered in public health and community settings: A systematic review.Canadian journal of public health = Revue canadienne de sante publique · 2017Pooled it
- Effects and safety of periconceptional oral folate supplementation for preventing birth defects.The Cochrane database of systematic reviews · 2015Pooled it
- Effects and safety of periconceptional folate supplementation for preventing birth defects.The Cochrane database of systematic reviews · 2010Pooled it
- Preconception Maternal Mentoring for Improved Fetal Growth among Indonesian Women: Results from a Cluster Randomized Controlled Trial.Nutrients · 2023Trial
- Acceptability and feasibility of a planned preconception weight loss intervention in women with long-acting reversible contraception: the Plan-it mixed-methods study.Health technology assessment (Winchester, England) · 2023Trial
- Computer-assisted provision of hormonal contraception in acute care settings.Contraception · 2013Trial
- Preconception care knowledge, attitudes, and practices among women attending a private women's hospital in Riyadh, Saudi Arabia: a cross-sectional study.Frontiers in global women's health · 2026Article
- Women's knowledge, attitudes and views of preconception health and intervention delivery methods: a cross-sectional survey.BMC pregnancy and childbirth · 2022Article
- Estimate of the potential impact of folic acid fortification of corn masa flour on the prevention of neural tube defects.Birth defects research. Part A, Clinical and molecular teratology · 2013Article
- Associations between preconception counseling and maternal behaviors before and during pregnancy.Maternal and child health journal · 2012Article
- Impact of a pharmacist-directed educational program on the long-term knowledge and use of folic acid among college women: a 12-month follow-up study.Pharmacy practice · 2012Article
- Factors contributing to the success of folic acid public health campaigns.Journal of public health (Oxford, England) · 2012Review
- Decreased incidence of myelomeningocele at birth: effect of folic acid recommendations or prenatal diagnostics?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2011Article
- Association between health beliefs and health behavior in early pregnancy.Maternal and child health journal · 2011Article
- Women's perspectives on counseling about risks for medication-induced birth defects.Birth defects research. Part A, Clinical and molecular teratology · 2010Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPericonception folate supplementation significantly reduces the risk of neural-tube defects, but few U.S. women start folate supplementation before pregnancy, and the amount of clinician time available to counsel patients about folate is limited. This study evaluated whether computer-assisted counseling and the provision of free folate tablets increases women's knowledge and use of folate supplements.
designRandomized controlled trial; follow-up began 6 months after enrollment and was completed on average 7 months after enrollment. SETTING/
participantsA total of 446 women, aged 18-45 years, were recruited from two urgent care clinics in San Francisco from March to July 2005 (data collection was completed in 2006; data were analyzed in 2007).
interventionParticipants received a 15-minute computerized educational session and 200 folate tablets.
main outcome measuresThe primary outcome was the knowledge that folate can prevent birth defects; secondary outcomes included the self-reported use of a folate supplement at follow-up.
resultsAt follow-up, women in the intervention group were more likely to know that folate prevents birth defects (46% vs 27%, relative risk [RR]=1.72, 95% CI=1.32, 2.23); to know that folate is most important in early pregnancy (36% vs 17%, RR=2.11, 95% CI=1.50, 2.97); and to report the recent use of a folate supplement (32% vs 21%, RR=1.54, 95% CI=1.12, 2.13).
conclusionsA one-time, brief, computerized counseling session about folate with the provision of free folate tablets increased the knowledge and use of folate supplements among women > or =6 months later.
trial registrationNCT00177515.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.