ArticleGenome biology2008
A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans.
Article in Genome biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 115 citations in OpenAlex.
- Close spatial and metabolic association between heterotrophic and ammonia-oxidizing marine Nitrososphaerota.ISME communications · 2026Article
- Elucidating the interplay between intracellular manganese-iron-ratio and radiotolerance across all domains of life.FEMS microbes · 2026Article
- Cooperation and Competition Were Primary Driving Forces for Biological Evolution.Microbial physiology · 2025Review
- Genesis of ectosymbiotic features based on commensalistic syntrophy.Scientific reports · 2024Article
- Bacterial genome size and gene functional diversity negatively correlate with taxonomic diversity along a pH gradient.Nature communications · 2023Article
- Comparative Genomic Insights into the Evolution ofmSystems · 2022Article
- Looking through the Lens of the Ribosome Biogenesis Evolutionary History: Possible Implications for Archaeal Phylogeny and Eukaryogenesis.Molecular biology and evolution · 2022Article
- Deciphering Symbiotic Interactions of "mSystems · 2021Article
- Comparative Genomics Provides Insights into the Genetic Diversity and Evolution of the DPANN Superphylum.mSystems · 2021Article
- Functional compartmentalization and metabolic separation in a prokaryotic cell.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Friends or Foes-Microbial Interactions in Nature.Biology · 2021Review
- A promiscuous ancestral enzyme´s structure unveils protein variable regions of the highly diverse metallo-β-lactamase family.Communications biology · 2021Article
- Indirect Routes to Aminoacyl-tRNA: The Diversity of Prokaryotic Cysteine Encoding Systems.Frontiers in genetics · 2021Article
- A spectrum of verticality across genes.PLoS genetics · 2020Article
- Microbial Strategies for Survival in the Glass SpongemSystems · 2020Article
- Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.Nature communications · 2020Article
- The hyperthermophilic partners Nanoarchaeum and Ignicoccus stabilize their tRNA T-loops via different but structurally equivalent modifications.Nucleic acids research · 2020Article
- Diversity, ecology and evolution of Archaea.Nature microbiology · 2020Review
- A Suggestion of Converting Protein Intrinsic Disorder to Structural Entropy Using Shannon's Information Theory.Entropy (Basel, Switzerland) · 2019Article
- Purification of a Crenarchaeal ATP Synthase in the Light of the Unique Bioenergetics ofJournal of bacteriology · 2019Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 10 institutions in 2 countries.
Funding
Abstract
backgroundThe relationship between the hyperthermophiles Ignicoccus hospitalis and Nanoarchaeum equitans is the only known example of a specific association between two species of Archaea. Little is known about the mechanisms that enable this relationship.
resultsWe sequenced the complete genome of I. hospitalis and found it to be the smallest among independent, free-living organisms. A comparative genomic reconstruction suggests that the I. hospitalis lineage has lost most of the genes associated with a heterotrophic metabolism that is characteristic of most of the Crenarchaeota. A streamlined genome is also suggested by a low frequency of paralogs and fragmentation of many operons. However, this process appears to be partially balanced by lateral gene transfer from archaeal and bacterial sources.
conclusionsA combination of genomic and cellular features suggests highly efficient adaptation to the low energy yield of sulfur-hydrogen respiration and efficient inorganic carbon and nitrogen assimilation. Evidence of lateral gene exchange between N. equitans and I. hospitalis indicates that the relationship has impacted both genomes. This association is the simplest symbiotic system known to date and a unique model for studying mechanisms of interspecific relationships at the genomic and metabolic levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.