Evidence map›Paper›PMID 18999991›Full record

ReviewAnnual review of physical chemistry2009

Active biological materials.

Daniel A Fletcher, Phillip L Geissler

Abstract readReview
In one paragraph

Review in Annual review of physical chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Metareview: a survey of active matter reviews.The European physical journal. E, Soft matter · 2025
    Review
  4. Electrochemical signaling for artificial innervation of self-oscillating gels.Science and technology of advanced materials · 2025
    Article
  5. Review
  6. Adaptive nonequilibrium design of actin-based metamaterials: Fundamental and practical limits of control.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. The Actin Cytoskeleton as an Active Adaptive Material.Annual review of condensed matter physics · 2020
    Article
  11. Article
  12. Active dumbbells: Dynamics and morphology in the coexisting region.The European physical journal. E, Soft matter · 2018
    Article
  13. Article
  14. Review
  15. Investigating cell mechanics with atomic force microscopy.Journal of the Royal Society, Interface · 2015
    Article
  16. Force fluctuations in three-dimensional suspended fibroblasts.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Article
  17. Emergent mechanics of biological structures.Molecular biology of the cell · 2014
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniel A FletcherDepartment of Bioengineering, University of California, Berkeley, California 94720, USA. fletch@berkeley.edu
Phillip L Geissler

Funding

Mechanical Regulation of Actin NetworksR01GM074751 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI FLETCHER, DANIEL A · 2008 to 2015
$2.4M
NIGMS NIH HHS R01 GM074751
6 · The paper itself

Abstract

Cells make use of dynamic internal structures to control shape and create movement. By consuming energy to assemble into highly organized systems of interacting parts, these structures can generate force and resist compression, as well as adaptively change in response to their environment. Recent progress in reconstituting cytoskeletal structures in vitro has provided an opportunity to characterize the mechanics and dynamics of filament networks formed from purified proteins. Results indicate that a complex interplay between length scales and timescales underlies the mechanical responses of these systems and that energy consumption, as manifested in molecular motor activity and cytoskeletal filament growth, can drive transitions between distinct material states. This review discusses the basic characteristics of these active biological materials that set them apart from conventional materials and that create a rich array of unique behaviors.

Indexed as

Biomechanical PhenomenaComputer SimulationMolecular Motor ProteinsTime FactorsMolecular Motor Proteins

Identifiers

PMID18999991
PMCPMC3236678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.