Evidence map›Paper›PMID 1899910›Full record

ArticleMolecular and cellular biology1991

Common factor 1 is a transcriptional activator which binds in the c-myc promoter, the skeletal alpha-actin promoter, and the immunoglobulin heavy-chain enhancer.

K J Riggs, K T Merrell, G Wilson, K Calame

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 83 citations in OpenAlex.

  1. Review
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  8. Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3.Proceedings of the National Academy of Sciences of the United States of America · 1996
    Article
  9. Article
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  11. YY1 and c-Myc associate in vivo in a manner that depends on c-Myc levels.Proceedings of the National Academy of Sciences of the United States of America · 1996
    Article
  12. Myc oncogenes: the enigmatic family.The Biochemical journal · 1996
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

K J RiggsDepartment of Biological Chemistry, University of California Los Angeles 90024.
K T Merrell
G Wilson
K Calame
University of California, Los Angeles · US

Funding

TRANSCRIPTION OF IMMUNOGLUBULIN HEAVY CHAIN GENESR01GM029361 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CALAME, KATHRYN L. · 1985 to 2001
$831k
C-MYC ONCOGENE REGULATION IN NORMAL AND MALIGNANT CELLSR01CA038571 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CALAME, KATHRYN L. · 1985 to 1992
–
NCI NIH HHS R01CA38571NIGMS NIH HHS R01GM29361
6 · The paper itself

Abstract

Ubiquitously expressed transcription factors play an integral role in establishing and regulating patterns of gene transcription. Common factor 1 (CF1) is a ubiquitously expressed DNA-binding protein previously identified in our laboratory. We show here that CF1 recognizes sites in several diverse transcription elements, and we demonstrate the ability of the c-myc CF1 site to activate transcription of a basal promoter in both B cells and fibroblasts.

Indexed as

Enhancer Elements, GeneticPromoter Regions, GeneticTranscription, GeneticActinsAnimalsBase SequenceDNA-Binding ProteinsGene Expression RegulationImmunoglobulin Heavy ChainsIn Vitro TechniquesMiceMolecular Sequence DataOligonucleotidesProto-Oncogene Proteins c-mycTranscription FactorsActinsDNA-Binding ProteinsImmunoglobulin Heavy ChainsOligonucleotidesProto-Oncogene Proteins c-mycTranscription Factors

Identifiers

PMID1899910
PMCPMC369495
OpenAlexW2107546950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.