Evidence map›Paper›PMID 18997841›Full record

ArticleThe Journal of investigative dermatology2008

Tumor evasion may occur via expression of regulatory molecules: a case for CTLA-4 in melanoma.

Jeffrey S Weber

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Immune Checkpoint Imaging in Oncology: A Game Changer Toward Personalized Immunotherapy?Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jeffrey S WeberH. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA. jeffrey.weber@moffitt.org
Moffitt Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging data that show immune-regulating molecules may be ectopically expressed on human tumors suggest that novel mechanisms may induce tumor-related immune suppression, and support the use of antibodies and small molecules to target those immune-suppressive moities.

Indexed as

AnimalsAntigens, CDCTLA-4 AntigenHumansImmune SystemLymphocyte ActivationMelanomaMiceNeoplasm InvasivenessPhenotypeSignal TransductionSkin NeoplasmsWnt ProteinsAntigens, CDCTLA-4 AntigenCTLA4 protein, humanCtla4 protein, mouseWnt Proteins

Identifiers

PMID18997841
OpenAlexW2031017289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.