ArticleAmerican journal of physiology. Heart and circulatory physiology2009
Multiresolution wavelet analysis of time-dependent physiological responses in syncopal youths.
Article in American journal of physiology. Heart and circulatory physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04976101 (A Pilot Study to Assess Sinusoidal Galvanic Vestibular Stimulation in Neurogenic Orthostatic Hypotension), which is not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study to Assess Sinusoidal Galvanic Vestibular Stimulation in Neurogenic Orthostatic Hypotension
Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- From Mechanism to Management in Vasovagal Syncope: An Integrative Review.Journal of clinical medicine · 2026Review
- Haemodynamic Patterns in Reflex Syncope: Insights from Head-Up Tilt Tests in Adults and Children.Journal of clinical medicine · 2025Article
- Predicting Vasovagal Responses: A Model-Based and Machine Learning Approach.Frontiers in neurology · 2021Article
- When Sinus Tachycardia Becomes Too Much: Negative Effects of Excessive Upright Tachycardia on Cardiac Output in Vasovagal Syncope, Postural Tachycardia Syndrome, and Inappropriate Sinus Tachycardia.Circulation. Arrhythmia and electrophysiology · 2020Article
- Vestibular, locomotor, and vestibulo-autonomic research: 50 years of collaboration with Bernard Cohen.Journal of neurophysiology · 2020Review
- Baroreflex Sensitivity Measured by Pulse Photoplethysmography.Frontiers in neuroscience · 2019Article
- Nitric oxide synthase inhibition restores orthostatic tolerance in young vasovagal syncope patients.Heart (British Cardiac Society) · 2017Article
- Vestibular Activation Habituates the Vasovagal Response in the Rat.Frontiers in neurology · 2017Article
- Heart Rate Spectra Confirm the Presence of Autonomic Dysfunction in Dementia Patients.Journal of Alzheimer's disease : JAD · 2016Article
- Postsynaptic α1-Adrenergic Vasoconstriction Is Impaired in Young Patients With Vasovagal Syncope and Is Corrected by Nitric Oxide Synthase Inhibition.Circulation. Arrhythmia and electrophysiology · 2016Article
- A Model of Blood Pressure, Heart Rate, and Vaso-Vagal Responses Produced by Vestibulo-Sympathetic Activation.Frontiers in neuroscience · 2016Article
- Vasovagal oscillations and vasovagal responses produced by the vestibulo-sympathetic reflex in the rat.Frontiers in neurology · 2014Article
- The vasovagal response of the rat: its relation to the vestibulosympathetic reflex and to Mayer waves.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2013Article
- Mechanisms of sympathetic regulation in orthostatic intolerance.Journal of applied physiology (Bethesda, Md. : 1985) · 2012Review
- Sinusoidal galvanic vestibular stimulation (sGVS) induces a vasovagal response in the rat.Experimental brain research · 2011Article
- Respiration drives phase synchronization between blood pressure and RR interval following loss of cardiovagal baroreflex during vasovagal syncope.American journal of physiology. Heart and circulatory physiology · 2011Article
- Increased phase synchronization and decreased cerebral autoregulation during fainting in the young.American journal of physiology. Heart and circulatory physiology · 2009Article
- Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome.American journal of physiology. Heart and circulatory physiology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Our prior studies indicated that postural fainting relates to thoracic hypovolemia. A supranormal increase in initial vascular resistance was sustained by increased peripheral resistance until late during head-up tilt (HUT), whereas splanchnic resistance, cardiac output, and blood pressure (BP) decreased throughout HUT. Our aim in the present study was to investigate the alterations of baroreflex activity that occur in synchrony with the beat-to-beat time-dependent changes in heart rate (HR), BP, and total peripheral resistance (TPR). We proposed that changes of low-frequency Mayer waves reflect sympathetic baroreflex. We used DWT multiresolution analyses to measure their time dependence. We studied 22 patients, 13 to 21 yr old, 14 who fainted within 10 min of upright tilt (fainters) and 8 healthy control subjects. Multiresolution analysis was obtained of continuous BP, HR, and respirations as a function of time during 70 degrees upright tilt at different scales corresponding to frequency bands. Wavelet power was concentrated in scales corresponding to 0.125 and 0.25 Hz. A major difference from control subjects was observed in fainters at the 0.125 Hz AP scale, which progressively decreased from early HUT. The alpha index at 0.125 Hz was increased in fainters. RR interval 0.25 Hz power decreased in fainters and controls but was markedly increased in fainters with syncope and thereafter corresponding to increased vagal tone compared with control subjects at those times only. The data imply a rapid reduction in time-dependent sympathetic baroreflex activity in fainters but not control subjects during HUT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.