ReviewBrain, behavior, and immunity2009
Three questions about leptin and immunity.
Review in Brain, behavior, and immunity, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 44 citations in OpenAlex.
- Trial
- Evaluation of Circulating Leptin and Its Receptor (Ob-R) Tissue Expression in Colorectal Cancer, a Report From North of Iran.Iranian journal of pathology · 2023Article
- Role of myeloid cell leptin signaling in the regulation of glucose metabolism.Scientific reports · 2021Article
- A novel leptin receptor antagonist uncouples leptin's metabolic and immune functions.Cellular and molecular life sciences : CMLS · 2019Article
- Leptin Functions in Infectious Diseases.Frontiers in immunology · 2018Review
- Endocrine and Metabolic Effects of Adipose Tissue in Children and Adolescents.Zdravstveno varstvo · 2015Review
- Insulin resistance and skin diseases.TheScientificWorldJournal · 2015Review
- Estrogen signaling in metabolic inflammation.Mediators of inflammation · 2014Review
- Leptin metabolically licenses T cells for activation to link nutrition and immunity.Journal of immunology (Baltimore, Md. : 1950) · 2014Article
- Article
- Generation of leptin receptor bone marrow chimeras: recovery from irradiation, immune cellularity, cytokine expression, and metabolic parameters.Obesity (Silver Spring, Md.) · 2010Article
- Effect of adiponectin deficiency on intestinal damage and hematopoietic responses of mice exposed to gamma radiation.Mutation research · 2010Article
- [Adipokine update - new molecules, new functions].Wiener medizinische Wochenschrift (1946) · 2010Review
- Effect of diet-induced obesity on acute pancreatitis induced by administration of interleukin-12 plus interleukin-18 in mice.Obesity (Silver Spring, Md.) · 2010Article
- Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.Journal of leukocyte biology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Leptin is a protein produced by adipocytes (and other cell types) that acts in the brain to regulate appetite and energy expenditure according to the amount of energy stored in adipose tissue. Leptin also exerts a variety of other functions, including important roles as a regulator of immune and inflammatory reactions. The present article is not meant to be a comprehensive review on leptin and immunity, but rather highlights a few controversial issues about leptin's place in the complex network of mediators regulating immune and inflammatory responses. Three issues are discussed: (1) Where am I going, or What is the cellular target of leptin for modulation of immune responses?; (2) Where am I coming from, or Is the cellular source important in determining leptin's effects on immune responses? and (3) What am I doing, or What are leptin's effects on immune and inflammatory responses?
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.