Evidence map›Paper›PMID 18996453›Full record

ReviewToxicology letters2009

Chemical databases for environmental health and clinical research.

Carolyn J Mattingly

Abstract readReview
In one paragraph

Review in Toxicology letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Aquatic models, genomics and chemical risk management.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2012
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Carolyn J MattinglyMount Desert Island Biological Laboratory, P.O. Box 35, Salisbury Cove, ME 04672, USA. cmattin@mdibl.org

Funding

WNT SIGNALING IN THE DEVELOPING GASTROINTESTINAL TRACTP20RR016463 · NCRR · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI WRAY, CHRISTOPHER C · 2001 to 2011
$41.0M
The Comparative Toxicogenomics Database (CTD)R01ES014065 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI DAVIS, ALLAN PETER, MATTINGLY, CAROLYN J. · 2006 to 2021
$10.5M
Generation of a centralized and integrated resource for exposure dataR01ES019604 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI MATTINGLY, CAROLYN J. · 2011 to 2015
$1.3M
NCRR NIH HHS P20 RR016463NCRR NIH HHS RR016463NIEHS NIH HHS ES014065NIEHS NIH HHS R01 ES014065NIEHS NIH HHS R01 ES019604
6 · The paper itself

Abstract

The increasing number of publicly available biological databases reflects the evolving need for managing and evaluating abundant and complex data in biological, clinical and computational research. Currently there are over 1000 biologically relevant databases in the public domain with varied content and diverse approaches to capturing and presenting data. This review summarizes the comparatively small niche of sophisticated databases and other resources that aim to enhance understanding of chemicals and their biological actions. The databases reviewed include 1 that emphasizes environmental chemicals and 9 that emphasize drugs and small molecules. These databases and their associated resources are incrementally strengthening the expanding field of toxicogenomics-based research by providing centralized sources of manually and computationally curated datasets and highly sophisticated tools for the meta-analysis of continually increasing environmental chemical, drug and small-molecule datasets.

Indexed as

Databases, FactualDrug-Related Side Effects and Adverse ReactionsEnvironmental HealthToxicogeneticsAnimalsEnvironmental ExposureEnvironmental MedicineEnvironmental PollutantsHumansEnvironmental Pollutants

Identifiers

PMID18996453
PMCPMC2727625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.