Evidence map›Paper›PMID 18996342›Full record

ReviewCell host & microbe2008

Molecular genetic manipulation of vector mosquitoes.

Olle Terenius, Osvaldo Marinotti, Douglas Sieglaff, Anthony A James

Abstract readReview
In one paragraph

Review in Cell host & microbe, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Intrinsic factors driving mosquito vector competence and viral evolution: a review.Frontiers in cellular and infection microbiology · 2023
    Review
  6. Review
  7. Transcriptome Analysis of anInternational journal of molecular sciences · 2022
    Article
  8. Article
  9. Insects · 2021
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. News from Africa: Novel Anopheline Species Transmit Plasmodium in Western Kenya.The American journal of tropical medicine and hygiene · 2016
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olle TereniusDepartment of Molecular Biology and Biochemistry, 3205 McGaugh Hall, University of California, Irvine, CA 92697, USA.
Osvaldo Marinotti
Douglas Sieglaff
Anthony A James

Funding

Species-specific regulated transposition in mosquitoesR01AI044238 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI JAMES, ANTHONY A. · 1999 to 2008
$3.1M
EXPRESSION OF EXOGENOUS GENES IN VECTOR MOSQUITOESR01AI029746 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI JAMES, ANTHONY A. · 1989 to 2006
$1.7M
NIAID NIH HHS R01 AI029746NIAID NIH HHS R01 AI044238
6 · The paper itself

Abstract

Genetic strategies for reducing populations of vector mosquitoes or replacing them with those that are not able to transmit pathogens benefit greatly from molecular tools that allow gene manipulation and transgenesis. Mosquito genome sequences and associated EST (expressed sequence tags) databases enable large-scale investigations to provide new insights into evolutionary, biochemical, genetic, metabolic, and physiological pathways. Additionally, comparative genomics reveals the bases for evolutionary mechanisms with particular focus on specific interactions between vectors and pathogens. We discuss how this information may be exploited for the optimization of transgenes that interfere with the propagation and development of pathogens in their mosquito hosts.

Indexed as

Host-Pathogen InteractionsAnimalsCulicidaeDatabases, Nucleic AcidDisease Transmission, InfectiousGene ExpressionGenome, InsectHumansInsect Vectors

Identifiers

PMID18996342
PMCPMC2656434

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.