Evidence map›Paper›PMID 18996340›Full record

ArticleCell host & microbe2008

Digest this! A role for autophagy in controlling pathogens.

Ryan J Whitmarsh, Christopher A Hunter

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. ATG5 Plays a Role inTransboundary and emerging diseases · 2026
    Article
  2. The Host Autophagy DuringFrontiers in microbiology · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ryan J WhitmarshDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 380 South University Avenue, Philadelphia, PA 19104, USA.
Christopher A Hunter
South University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy provides a mechanism for cells to conserve nutrients, but was recently associated with immunity to intracellular pathogens. Here, Zhao et al. (2008) present direct in vivo evidence that autophagy is linked to macrophage control of Toxoplasma gondii and Listeria monocytogenes and highlights that this process intersects with cytokine-mediated antimicrobial responses.

Indexed as

AutophagyAnimalsAutophagy-Related Protein 5Host-Pathogen InteractionsHumansListeria monocytogenesListeriosisMacrophagesMicrotubule-Associated ProteinsToxoplasmaToxoplasmosisAtg5 protein, mouseAutophagy-Related Protein 5Microtubule-Associated Proteins

Identifiers

PMID18996340
OpenAlexW1984770662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.