Evidence map›Paper›PMID 18995875›Full record

ReviewVirology2009

The role of polyomaviruses in human disease.

Mengxi Jiang, Johanna R Abend, Silas F Johnson, Michael J Imperiale

Open access · greenAbstract readReview
In one paragraph

Review in Virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 288 citations in OpenAlex.

  1. Prospective Study of Human Polyomaviruses and Risk of Cutaneous Squamous Cell Carcinoma in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016
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80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mengxi JiangDepartment of Microbiology and Immunology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, 48109, USA.
Johanna R Abend
Silas F Johnson
Michael J Imperiale
University of Michigan · US

Funding

PREDOCTORAL TRAINING IN GENETICST32GM007544 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORAN, JOHN V. · 1985 to 2022
$11.3M
Training Program in Tumor MicroenvironmentT32CA009676 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Maria G Castro, Analisa Virginia DiFeo · 1992 to 2026
$7.3M
Parameters Governing Kidney Cell Infection with BKVR01AI060584 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI IMPERIALE, MICHAEL J. · 2004 to 2020
$4.8M
BK Virus as a Co-Factor in Prostate CancerR01CA118970 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI IMPERIALE, MICHAEL J. · 2007 to 2009
$855k
NCI NIH HHS CA118970NCI NIH HHS R01 CA118970NCI NIH HHS T32 CA009676NCI NIH HHS T32-CA009676NIAID NIH HHS AI060584NIAID NIH HHS R01 AI060584NIGMS NIH HHS T32 GM007544
6 · The paper itself

Abstract

The human polyomaviruses, BK virus and JC virus, have long been associated with serious diseases including polyomavirus nephropathy and progressive multifocal leukoencephalopathy. Both viruses establish ubiquitous, persistent infections in healthy individuals. Reactivation can occur when the immune system is impaired, leading to disease progression. Recently, the human polyomavirus family has expanded with the identification of three new viruses (KI, WU and Merkel cell polyomavirus), all of which may prove to be involved in human disease. This review describes the general aspects of human polyomavirus infections and pathogenicity. Current topics of investigation and future directions in the field are also discussed.

Indexed as

BK VirusHumansJC VirusKidney DiseasesLeukoencephalopathy, Progressive MultifocalMultiple SclerosisNeoplasmsPolyomavirusPolyomavirus InfectionsTumor Virus Infections

Identifiers

PMID18995875
PMCPMC2661150
OpenAlexW2027674723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.