Evidence map›Paper›PMID 18992173›Full record

ReviewBMC infectious diseases2008

Streptococcus intermedius causing infective endocarditis and abscesses: a report of three cases and review of the literature.

MaryAnn P Tran, Molly Caldwell-McMillan, Walid Khalife, Vincent B Young

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Osteomyelitis caused by Streptococcus intermedius in immunocompetent adults - a case report and systematic literature review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Pooled it
  2. Article
  3. Article
  4. Frontiers in cellular and infection microbiology · 2025
    Review
  5. Article
  6. Oral streptococciInfection and immunity · 2024
    Article
  7. Brain Abscess due toCase reports in pediatrics · 2024
    Article
  8. Infectious disease reports · 2023
    Article
  9. Lung abscess due toClinical case reports · 2023
    Article
  10. Clinical features ofFrontiers in microbiology · 2023
    Article
  11. Article
  12. An isolated pulmonary nodule secondary toFrontiers in pediatrics · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

MaryAnn P TranDepartment of Medicine, Infectious Diseases Division, Michigan State University, East Lansing, Michigan, USA. maryann.tran@hc.msu.edu
Molly Caldwell-McMillan
Walid Khalife
Vincent B Young
Michigan State University · USSparrow Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStreptococcus intermedius is a member of the Streptococcus anginosus group. Clinical disease with S. intermedius is characterized by abscess formation and rarely endocarditis. Identification of Streptococcus intermedius is difficult, leading to the development of molecular methods to more accurately identify and characterize this organism. CASE PRESENTATION: Over a period of 6 months we encountered three cases of invasive Streptococcus intermedius infection presenting as hepatic abscesses, brain abscess, and endocarditis. We confirmed our microbiologic diagnosis through 16S sequencing and found a common virulence gene in each case.

conclusionOur report illustrates three different clinical manifestations due to Streptococcus intermedius infection that can be encountered in healthy individuals in a community hospital setting. To our knowledge, this is the first case of Streptococcus intermedius endocarditis confirmed by 16S sequencing analysis. The use of molecular methods may allow a better understanding of the epidemiology and pathogenesis of this organism.

Indexed as

AdolescentAdultBacterial ProteinsBrain AbscessEndocarditis, BacterialFemaleHumansLiver AbscessMaleMiddle AgedRNA, BacterialRNA, Ribosomal, 16SSequence Analysis, DNAStreptococcal InfectionsStreptococcus intermediusVirulence FactorsBacterial ProteinsRNA, BacterialRNA, Ribosomal, 16SVirulence Factors

Identifiers

PMID18992173
PMCPMC2600825
OpenAlexW2089626398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.