ArticleWorld journal of emergency surgery : WJES2008
Spectrum of perforation peritonitis in Pakistan: 300 cases Eastern experience.
Article in World journal of emergency surgery : WJES, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 114 citations in OpenAlex.
- Emergency surgery score as a predictor of postoperative surgical site infection in patients undergoing emergency surgery for gastrointestinal diseases: A prospective cohort study.Pakistan journal of medical sciences · 2026Article
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- Clinical profile and management of perforation peritonitis in Bharatpur hospital, Nepal: A prospective study.Annals of medicine and surgery (2012) · 2022Article
- Article
- Use of a Clinical Audit System in Implementing Surviving Sepsis Campaign Guidelines in Patients With Peritonitis.Cureus · 2021Article
- Article
- A differentiated approach to repeat small-bowel anastomoses in patients with postoperative peritonitis: a prospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Article
- Emerging Spectrum of Perforation Peritonitis in Developing World.Frontiers in surgery · 2020Article
- Wound Outcome Following Primary and Delayed Primary Skin Closure Techniques After Laparotomy for Non-Traumatic Ileal Perforation: a Randomized Clinical Trial.The Indian journal of surgery · 2017Article
- Article
- Comparison of antimicrobial resistance patterns of ESBL and non ESBL bacterial isolates among patients with secondary peritonitis at Bugando Medical Centre, Mwanza - Tanzania.BMC emergency medicine · 2016Article
- Which cause of diffuse peritonitis is the deadliest in the tropics? A retrospective analysis of 305 cases from the South-West Region of Cameroon.World journal of emergency surgery : WJES · 2016Article
- Postoperative Morbidity and Mortality of Perforated Peptic Ulcer: Retrospective Cohort Study of Risk Factors among Black Africans in Côte d'Ivoire.Gastroenterology research and practice · 2016Article
- Etiology, treatment outcome and prognostic factors among patients with secondary peritonitis at Bugando Medical Centre, Mwanza, Tanzania.World journal of emergency surgery : WJES · 2015Article
- Spectrum of perforation peritonitis.Journal of clinical and diagnostic research : JCDR · 2013Article
- Anesthetic management for patients with perforation peritonitis.Journal of anaesthesiology, clinical pharmacology · 2013Review
- An audit of secondary peritonitis at a tertiary care university hospital of Sindh, Pakistan.World journal of emergency surgery : WJES · 2012Article
- Preoperative predictors of mortality in adult patients with perforation peritonitis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2011Article
- Validation of the use of POSSUM score in enteric perforation peritonitis - results of a prospective study.The Pan African medical journal · 2011Article
- Multiple intestinal perforations as a primary manifestation of abdominal tuberculosis in a HIV-infected patient.Journal of surgical case reports · 2010Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPerforation peritonitis is the most common surgical emergency encountered by the surgeons all over the world as well in Pakistan. The spectrum of etiology of perforation peritonitis in tropical countries continues to differ from its western counter part. This study was conducted at Dow University of health sciences and Civil Hospital Karachi (DUHS & CHK) Pakistan, designed to highlight the spectrum of perforation peritonitis in the East and to improve its outcome.
methodsA prospective study includes three hundred consecutive patients of perforation peritonitis studied in terms of clinical presentations, Causes, site of perforation, surgical treatment, post operative complications and mortality, at (DUHS&CHK) Pakistan, from 1st September 2005 - 1st March 2008, over a period of two and half years. All patients were resuscitated underwent emergency exploratory laparotomy. On laparotomy cause of perforation peritonitis was found and controlled.
resultsThe most common cause of perforation peritonitis noticed in our series was acid peptic disease 45%, perforated duodenal ulcer (43.6%) and gastric ulcer 1.3%. followed by small bowel tuberculosis (21%) and typhoid (17%). large bowel perforation due to tuberculosis 5%, malignancy 2.6% and volvulus 0.3%. Perforation due to acute appendicitis (5%). Highest number of perforations has seen in the duodenum 43.6%, ileum37.6%, and colon 8%, appendix 5%, jejunum 3.3%, and stomach 2.3%. Overall mortality was (10.6%).
conclusionThe spectrum of perforation peritonitis in Pakistan continuously differs from western country. Highest number of perforations noticed in the upper part of the gastrointestinal tract as compared to the western countries where the perforations seen mostly in the distal part. Most common cause of perforation peritonitis is perforated duodenal ulcer, followed by small bowel tuberculosis and typhoid perforation. Majority of the large bowel perforations are also tubercular. Malignant perforations are least common in our setup.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.