Evidence map›Paper›PMID 18992146›Full record

ArticleInternational archives of medicine2008

Pulmonary bacterial pathogens in cystic fibrosis patients and antibiotic therapy: a tool for the health workers.

Henrique Douglas M Coutinho, Vivyanne S Falcão-Silva, Gregório Fernandes Gonçalves

Open access · diamondAbstract read
In one paragraph

Article in International archives of medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Molecular Regulation of Biofilm Development inPathogens (Basel, Switzerland) · 2026
    Review
  3. Regulation of interbacterial interactions betweenbioRxiv : the preprint server for biology · 2026
    Article
  4. Interplay ofVirulence · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Acute Pericarditis in an Adult with Cystic Fibrosis: A Case Report and Literature Review.European journal of case reports in internal medicine · 2025
    Article
  9. Article
  10. Insights intoJournal of fungi (Basel, Switzerland) · 2024
    Article
  11. Frontiers in microbiology · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Role of inhaled antibiotics in the era of highly effective CFTR modulators.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  17. Article
  18. Molecular targets for cystic fibrosis and therapeutic potential of monoclonal antibodies.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Henrique Douglas M CoutinhoLaboratório de Pesquisa em Produtos Naturais, Departamento de Ciências físicas e Biológicas, Centro de Ciências Biológicas e da Saúde, Universidade Regional do Cariri, Crato (CE), Brazil. hdmcoutinho@gmail.com.
Vivyanne S Falcão-Silva
Gregório Fernandes Gonçalves
Universidade Federal da Paraíba · BRUniversidade Regional do Cariri · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis is the most common and best known genetic disease involving a defect in transepithelial Cl- transport by mutations in the CF gene on chromosome 7, which codes for the cystic fibrosis transmembrane conductance regulator protein (CFTR). The most serious symptoms are observed in the lungs, augmenting the risk of bacterial infection. The objective of this review was to describe the bacterial pathogens colonizing patients with cystic fibrosis. A systematic search was conducted using the international bibliographic databanks SCIELO, HIGHWIRE, PUBMED, SCIRUS and LILACS to provide a useful and practical review for healthcare workers to make them aware of these microorganisms. Today, B. cepacia, P. aeruginosa and S. aureus are the most important infectious agents in cystic fibrosis patients. However, healthcare professionals must pay attention to emerging infectious agents in these patients, because they represent a potentially serious future problem. Therefore, these pathogens should be pointed out as a risk to these patients, and hospitals all over the world must be prepared to detect and combat these bacteria.

Identifiers

PMID18992146
PMCPMC2586015
OpenAlexW2000668325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.