ArticleJapanese journal of ophthalmology
Changes in muscle fiber size and in the composition of myosin heavy chain isoforms of rabbit extraocular rectus muscle following recession surgery.
Article in Japanese journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- One-Month-Old Rabbits Exhibit a Longer Postoperative Remodeling in Extraocular Muscles Compared to 3-Month-Old Rabbits.Investigative ophthalmology & visual science · 2025Article
- Increased vertical dimension effects on masseter muscle fiber phenotype during maturation.The Angle orthodontist · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the changes in the size of muscle fibers and the composition of myosin heavy chain (MyHC) isoforms in the global layer (GL) and the orbital layer (OL) of rabbit rectus extraocular muscle (EOM) after recession.
methodsThe right superior rectus muscles of two rabbits were harvested at 3 days or 1, 2, or 4 weeks after recession (eight rabbits in total). At each time point, one muscle was used for measuring the cross-sectional area of the muscle fibers and the other for identifying the composition of MyHC. The right superior rectus muscles of three additional naïve rabbits were used as controls.
resultsThe mean cross-sectional area of the OL fibers did not change significantly. However, that of the GL fibers significantly decreased at 3 days (P<0.001) and 1 week (P=0.024) postoperatively, and increased thereafter to reach the control levels at 2 and 4 weeks postoperatively. Three days after surgery, the total MyHC content and the proportion of type IIb MyHC (MyHCIIb) plus EOM-specific MyHC (MyHCeom) decreased and remained at its lower level for 4 weeks.
conclusionsTransient atrophy and regeneration were observed only in the GL, and the changes in the MyHCIIb plus MyHCeom appeared to be related to these changes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.