Evidence map›Paper›PMID 18990964›Full record

ReviewInternational journal of chronic obstructive pulmonary disease2008

Medication adherence issues in patients treated for COPD.

Ruben D Restrepo, Melissa T Alvarez, Leonard D Wittnebel, Helen Sorenson, Richard Wettstein, David L Vines, Jennifer Sikkema-Ortiz, Donna D Gardner, Robert L Wilkins

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of chronic obstructive pulmonary disease, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

173 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  16. Adjunctive treatment with oral AKL1, a botanical nutraceutical, in chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2014
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  20. Delivery characteristics and patients' handling of two single-dose dry-powder inhalers used in COPD.International journal of chronic obstructive pulmonary disease · 2011
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113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ruben D RestrepoDepartment of Respiratory Care, The University of Texas Health Science Center at San Antonio,Texas 78229, USA. restrepor@uthscsa.edu
Melissa T Alvarez
Leonard D Wittnebel
Helen Sorenson
Richard Wettstein
David L Vines
Jennifer Sikkema-Ortiz
Donna D Gardner
Robert L Wilkins

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although medical treatment of COPD has advanced, nonadherence to medication regimens poses a significant barrier to optimal management. Underuse, overuse, and improper use continue to be the most common causes of poor adherence to therapy. An average of 40%-60% of patients with COPD adheres to the prescribed regimen and only 1 out of 10 patients with a metered dose inhaler performs all essential steps correctly. Adherence to therapy is multifactorial and involves both the patient and the primary care provider. The effect of patient instruction on inhaler adherence and rescue medication utilization in patients with COPD does not seem to parallel the good results reported in patients with asthma. While use of a combined inhaler may facilitate adherence to medications and improve efficacy, pharmacoeconomic factors may influence patient's selection of both the device and the regimen. Patient's health beliefs, experiences, and behaviors play a significant role in adherence to pharmacological therapy. This manuscript reviews important aspects associated with medication adherence in patients with COPD and identifies some predictors of poor adherence.

Indexed as

Medication AdherenceEconomics, PharmaceuticalHealth BehaviorHospitalizationHumansMetered Dose InhalersPatient Education as TopicPatient SatisfactionPulmonary Disease, Chronic ObstructiveQuality of Life

Identifiers

PMID18990964
PMCPMC2629978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.