SynthesisSchizophrenia bulletin2010
Rates of homicide during the first episode of psychosis and after treatment: a systematic review and meta-analysis.
Synthesis in Schizophrenia bulletin, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 7 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Systematic Review and Meta-Analysis: Risk Factors of Violence During First-Episode Psychosis.Trauma, violence & abuse · 2026Pooled it
- Systematic Review and Meta-analysis: Rates of Violence During First-Episode Psychosis (FEP).Schizophrenia bulletin · 2024Pooled it
- Systematic review and meta-analysis of homicide recidivism and schizophrenia.BMC psychiatry · 2014Pooled it
- Comorbid depressive and anxiety disorders in 509 individuals with an at-risk mental state: impact on psychopathology and transition to psychosis.Schizophrenia bulletin · 2014Pooled it
- At risk for schizophrenic or affective psychoses? A meta-analysis of DSM/ICD diagnostic outcomes in individuals at high clinical risk.Schizophrenia bulletin · 2013Pooled it
- Psychotic disorders and repeat offending: systematic review and meta-analysis.Schizophrenia bulletin · 2011Pooled it
- Homicide of strangers by people with a psychotic illness.Schizophrenia bulletin · 2011Pooled it
- Forensic mental health service use in early psychosis: A scoping review.Social psychiatry and psychiatric epidemiology · 2026Review
- Orbitofrontal functional network: the mediating role between violence and childhood trauma in patients with schizophrenia.Schizophrenia (Heidelberg, Germany) · 2025Article
- Neurological soft signs and sociodemographic and clinical characteristics among patients with schizophrenia with and without a history of violence.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2025Article
- Establishing a long-term predictive model for aggressive behavior in schizophrenia: a 21-year longitudinal study in rural China.Frontiers in psychiatry · 2025Article
- Updated rationale for the initial antipsychotic selection for patients with schizophrenia.Schizophrenia (Heidelberg, Germany) · 2024Review
- Exploring Characteristics of Homicide Offenders With Schizophrenia Spectrum Disorders Via Machine Learning.International journal of offender therapy and comparative criminology · 2024Article
- TheFrontiers in psychiatry · 2024Article
- Homicide in the context of psychosis: analysis of prior service utilisation and age at onset of illness and violence.BJPsych open · 2023Article
- Socio-demographic, clinical and offense-related characteristics of forensic psychiatric inpatients in Hunan, China: a cross-sectional survey.BMC psychiatry · 2023Article
- Risk factors for violence among female forensic inpatients with schizophrenia.Frontiers in psychiatry · 2023Article
- Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysis.Annals of general psychiatry · 2022Review
- Effectiveness of Artificial Intelligence Methods in Personalized Aggression Risk Prediction within Inpatient Psychiatric Treatment Settings-A Systematic Review.Journal of personalized medicine · 2022Review
- Effects of Integrated Moral Reasoning Development Intervention for Management of Violence in Schizophrenia: A Randomized Controlled Trial.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The observation that almost half of the homicides committed by people with a psychotic illness occur before initial treatment suggests an increased risk of homicide during the first episode of psychosis. The aim of this study was to estimate the rates of homicide during the first episode of psychosis and after treatment. A systematic search located 10 studies that reported details of all the homicide offenders with a psychotic illness within a known population during a specified period and reported the number of people who had received treatment prior to the offense. Meta-analysis of these studies showed that 38.5% (95% confidence interval [CI] = 31.1%-46.5%) of homicides occurred during the first episode of psychosis, prior to initial treatment. Homicides during first-episode psychosis occurred at a rate of 1.59 homicides per 1000 (95% CI = 1.06-2.40), equivalent to 1 in 629 presentations. The annual rate of homicide after treatment for psychosis was 0.11 homicides per 1000 patients (95% CI = 0.07-0.16), equivalent to 1 homicide in 9090 patients with schizophrenia per year. The rate ratio of homicide in the first episode of psychosis in these studies was 15.5 (95% CI = 11.0-21.7) times the annual rate of homicide after treatment for psychosis. Hence, the rate of homicide in the first episode of psychosis appears to be higher than previously recognized, whereas the annual rate of homicide by patients with schizophrenia after treatment is lower than previous estimates. Earlier treatment of first-episode psychosis might prevent some homicides.
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