ArticleHead & face medicine2008
Osseointegration of zirconia implants: an SEM observation of the bone-implant interface.
Article in Head & face medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.
- A systematic review of the clinical survival of zirconia implants.Clinical oral investigations · 2016Pooled it
- A prospective clinical study to evaluate the performance of zirconium dioxide dental implants in single-tooth edentulous area: 3-year follow-up.BMC oral health · 2018Trial
- Innovations in Implant Osseointegration: Biomaterials, Surface Engineering, and Translational Strategies.Journal of biomedical materials research. Part A · 2026Review
- The impact of physiological and parafunctional posterior occlusal forces on experimental Ti-15Zrsupracrestal dental implant - a finite element analysis.Medicine and pharmacy reports · 2025Article
- Pre-implantation teriparatide administration improves initial implant stability and accelerates the osseointegration process in osteoporotic rats.International journal of implant dentistry · 2024Article
- Review
- In Vivo Biofilm Formation on Novel PEEK, Titanium, and Zirconia Implant Abutment Materials.International journal of molecular sciences · 2023Article
- Evaluation of stress and deformation in bone with titanium, CFR-PEEK and zirconia ceramic implants by finite element analysis.Dental research journal · 2023Article
- Early bone formation around immediately placed two-piece tissue-level zirconia implants with a modified surface: an experimental study in the miniature pig mandible.International journal of implant dentistry · 2022Article
- Contemporary Concepts in Osseointegration of Dental Implants: A Review.BioMed research international · 2022Review
- The Impact of EBM-Manufactured Ti6Al4V ELI Alloy Surface Modifications on Cytotoxicity toward Eukaryotic Cells and Microbial Biofilm Formation.Materials (Basel, Switzerland) · 2020Article
- Osteoclastogenesis Behavior of Zirconia for Dental Implant.Materials (Basel, Switzerland) · 2019Article
- Manual polishing of 3D printed metals produced by laser powder bed fusion reduces biofilm formation.PloS one · 2019Article
- Application of combined porous tantalum scaffolds loaded with bone morphogenetic protein 7 to repair of osteochondral defect in rabbits<sup/>.International orthopaedics · 2018Article
- Comparative study of new bone formation capability of zirconia bone graft material in rabbit calvarial.The journal of advanced prosthodontics · 2018Article
- Two-piece zirconia implants supporting all-ceramic crowns: a prospective clinical study.Clinical oral implants research · 2015Article
- A Critical Review of Dental Implant Materials with an Emphasis on TitaniumMaterials (Basel, Switzerland) · 2015Review
- Zirconia Implants in Esthetic Areas: 4-Year Follow-Up Evaluation Study.International journal of dentistry · 2015Article
- Zirconium, calcium, and strontium contents in magnesium based biodegradable alloys modulate the efficiency of implant-induced osseointegration.International journal of nanomedicine · 2013Article
- Evaluation of the success criteria for zirconia dental implants: a four-year clinical and radiological study.International journal of dentistry · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe successful use of zirconia ceramics in orthopedic surgery led to a demand for dental zirconium-based implant systems. Because of its excellent biomechanical characteristics, biocompatibility, and bright tooth-like color, zirconia (zirconium dioxide, ZrO2) has the potential to become a substitute for titanium as dental implant material. The present study aimed at investigating the osseointegration of zirconia implants with modified ablative surface at an ultrastructural level.
methodsA total of 24 zirconia implants with modified ablative surfaces and 24 titanium implants all of similar shape and surface structure were inserted into the tibia of 12 Göttinger minipigs. Block biopsies were harvested 1 week, 4 weeks or 12 weeks (four animals each) after surgery. Scanning electron microscopy (SEM) analysis was performed at the bone implant interface.
resultsRemarkable bone attachment was already seen after 1 week which increased further to intimate bone contact after 4 weeks, observed on both zirconia and titanium implant surfaces. After 12 weeks, osseointegration without interposition of an interfacial layer was detected. At the ultrastructural level, there was no obvious difference between the osseointegration of zirconia implants with modified ablative surfaces and titanium implants with a similar surface topography.
conclusionThe results of this study indicate similar osseointegration of zirconia and titanium implants at the ultrastructural level.
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