ArticleJournal of assisted reproduction and genetics
Clinical outcome of frozen blastocyst transfer; single vs. double transfer.
Article in Journal of assisted reproduction and genetics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 31 citations in OpenAlex.
- Pregnancy outcomes following in vitro fertilization treatment in women with previous recurrent ectopic pregnancy.PloS one · 2022Article
- Effect of Age and Embryo Morphology on Live Birth Rate After Transfer of Unbiopsied Blastocysts.JBRA assisted reproduction · 2021Article
- An abdominal ectopic pregnancy following a frozen-thawed ART cycle: a case report and review of the literature.BMC pregnancy and childbirth · 2017Review
- A retrospective study of single frozen-thawed blastocyst transfer.Clinical and experimental reproductive medicine · 2016Article
- Single vitrified blastocyst transfer maximizes liveborn children per embryo while minimizing preterm birth.Fertility and sterility · 2015Article
- Comparison of clinical outcomes between single and double vitrified-warmed blastocyst embryo transfer according to the day of vitrification.Journal of assisted reproduction and genetics · 2013Article
- A case report of bilateral tubal ectopic pregnancy following day 5 embryo transfer.Archives of medical science : AMS · 2011Article
- Comparison between Cleavage Stage versus Blastocyst Stage Embryo Transfer in an Egyptian Cohort Undergoing in vitro Fertilization: A Possible Role for Laser Assisted Hatching.Clinical medicine insights. Reproductive health · 2011Article
- Frozen-thawed embryo transfer cycles: clinical outcomes of single and double blastocyst transfers.Journal of assisted reproduction and genetics · 2011Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFrozen embryo transfer has been established as an indispensable ART procedure for both the effective use of surplus embryos and the prevention of ovarian hyperstimulation syndrome. The frequency of frozen embryo transfer is increasing in our clinic, and we report that frozen embryo transfer is effective for patients with repeat failures. We present our clinical outcome of frozen blastocyst transfer (FBT).
methodsIn 2006, 470 patients received FBT (562 cycles (IVF: 354 cycles; ICSI: 208 cycles)). One frozen blastocyst was transferred in 412 cycles (335 patients) and two blastocysts were transferred in 150 cycles (135 patients). Assisted hatching was performed in all cases.
resultsIn 412 cycles (average age: 34.6 years) who received a single FBT, the rate of clinical pregnancy per cycle was 40.7%, the live birth rate was 29.1%, the abortion rate was 21.6%, the ectopic pregnancy rate was 1.2%, the frequency of monochorionic twins was 2.3%, and the cesarean section rate was 38.3%. In 150 cycles (average patient age 34.8 years) who received two FBTs, the clinical pregnancy rate was 46%, the live birth rate was 35.3%, the abortion rate was 16.3%, the ectopic pregnancy rate was 4.4%, the frequency of twins was 15.9% and the cesarean section rate was 39.6%. A significant difference in the ectopic pregnancy rate and the twinning rate was found between single transfers and double transfers (P < 0.05). When IVF and ICSI were compared, there was no statistically significant difference in the abortion rate, the ectopic pregnancy rate, and the cesarean section rate.
conclusionsThe clinical pregnancy rate was similar for the transfer of one and two blastocysts. Single FBT decreases obstetrical risk without reducing the pregnancy rate.
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