Evidence map›Paper›PMID 18989696›Full record

ReviewLangenbeck's archives of surgery2009

Reflux esophagitis, high-grade neoplasia, and early Barrett's carcinoma-what is the place of the Merendino procedure?

A H Hölscher, D Vallböhmer, C Gutschow, E Bollschweiler

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Langenbeck's archives of surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02855333 (The Merendino Procedure for Benign or Early Malignant Lesions of the Distal Esophagus/Gastroesophageal Junction is Feasible, Safe and Provides Good QoL), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02855333 completednot on this mapstarted 2014, after this paper: background citation

The Merendino Procedure for Benign or Early Malignant Lesions of the Distal Esophagus/Gastroesophageal Junction is Feasible, Safe and Provides Good QoL

TypeobservationalSponsorKantonsspital LiestalRan2014 to 2016Enrolled26ConditionsBenign or Early Malignant Lesion of the Distal Esophagus or Gastro-esophageal Junction Requiring Surgical ResectionArmsEORTC and QLQ-C30 / QLQ-OES24 questionnaire
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. [A rare vascular variation with great importance in esophageal surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2019
    Article
  2. Article
  3. [Surgical strategy for early stage carcinoma of the esophagus].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018
    Review
  4. Article
  5. Article
  6. Management strategies of Barrett's esophagus.World journal of gastroenterology · 2012
    Review
  7. Article
  8. Esophageal leiomyomatosis combined with intrathoracic stomach and gastric volvulus.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A H HölscherDepartment of General, Visceral and Cancer Surgery, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany. Arnulf.Hoelscher@uk-koeln.de
D Vallböhmer
C Gutschow
E Bollschweiler
University of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBecause of the increasing frequency of Barrett's cancer in Western industrialized countries, the management of reflux disease with the potential development of Barrett's esophagus, neoplasia, and early carcinoma is very important. In case of established Barrett's esophagus, the malignant degeneration of the specialized epithelium cannot definitely be prevented by antireflux surgery or continuous medication. Mucosal adenocarcinomas nearly never develop lymph node metastasis and can mostly be treated by endoscopic mucosectomy. The deeper the submucosa is infiltrated, the higher is the rate of lymph node metastasis which is, on the average, 30% for submucosal carcinoma.

conclusionsTherefore, radical subtotal esophagectomy is the treatment of choice for submucosal carcinoma, whereas distal esophageal resection with limited lymph node dissection is only indicated in mucosal carcinoma which cannot be completely removed by interventional endoscopy.

Indexed as

AdenocarcinomaBarrett EsophagusEsophageal NeoplasmsEsophagectomyEsophagitis, PepticEsophagoscopyHumansLymph Node ExcisionPrecancerous Conditions

Identifiers

PMID18989696
OpenAlexW2050679591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.