ArticleEuropean journal of applied physiology2009
Modulation of heart rate variability by estrogen in young women undergoing induction of ovulation.
Article in European journal of applied physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Correlation between heart rate variability and estradiol, progesterone, and the estradiol/progesterone ratio across menstrual phases in healthy women.Physiological reports · 2026Article
- Cardiac Function in Women with and Without Previous Assisted Reproductive Technology: A Prospective Observational Cohort Study.Journal of clinical medicine · 2025Article
- Cardiorespiratory response to exercise in endurance-trained premenopausal and postmenopausal females.European journal of applied physiology · 2021Article
- Sex Differences in the Physiological Network of Healthy Young Subjects.Frontiers in physiology · 2021Article
- Assessing heart rate variability in type 1 diabetes mellitus-Psychosocial stress a possible confounder.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020Article
- Menstrual Cycle Changes in Vagally-Mediated Heart Rate Variability are Associated with Progesterone: Evidence from Two Within-Person Studies.Journal of clinical medicine · 2020Article
- A Systematic Review and Meta-Analysis of Within-Person Changes in Cardiac Vagal Activity across the Menstrual Cycle: Implications for Female Health and Future Studies.Journal of clinical medicine · 2019Review
- Cardiovascular Autonomic Profile in Women With Premenstrual Syndrome.Frontiers in physiology · 2018Article
- Effects of ovarian hormones and oral contraceptive pills on cardiac vagal withdrawal at the onset of dynamic exercise.PloS one · 2015Article
- Autonomic regulation across phases of the menstrual cycle and sleep stages in women with premenstrual syndrome and healthy controls.Psychoneuroendocrinology · 2013Article
- Bradycardic effects mediated by activation of G protein-coupled estrogen receptor in rat nucleus ambiguus.Experimental physiology · 2013Article
- Unexpected course of nonlinear cardiac interbeat interval dynamics during childhood and adolescence.PloS one · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Estrogens are involved in the modulation of the cardiovascular system, yet their effects in young women remains largely unknown. Women who undergo ovulation induction treatments attain extremely high estrogen concentrations during a very short time period. The aim of the present study was to evaluate the effects of an acute increase in estrogens on the autonomic nervous system modulation of heart rate variability (HRV). A total of 27 women undergoing ovulation induction and 14 normally menstruating women were prospectively studied. HRV was assessed during nadir and peak estrogen using time domain and power spectral density analyses. A significant increase in high-frequency spectral power (243 +/- 77 vs. 188 +/- 73 ms(2)/Hz, P < 0.01) with a significant decrease in the ratio of low to high-frequency power was observed during estrogen peak in women undergoing induction of ovulation. The acute increase in estrogen in women undergoing ovulation induction was associated with vagal activation and altered sympathovagal balance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.