Evidence map›Paper›PMID 18989651›Full record

ArticleDer Anaesthesist2008

[Non-invasive ventilation as treatment for acute respiratory insufficiency. Essentials from the new S3 guidelines].

B Schönhofer, R Kuhlen, P Neumann, M Westhoff, C Berndt, H Sitter

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Der Anaesthesist, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Guideline
  2. Review
  3. [Extreme obesity-particular aspect of invasive and noninvasive ventilation].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2019
    Review
  4. High Levels of Soluble Triggering Receptor Expressed on Myeloid Cells-Like Transcript (TLT)-1 Are Associated With Acute Respiratory Distress Syndrome.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018
    Article
  5. Article
  6. Article
  7. [Preventable mistakes during endotracheal intubation. Overview and concepts].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2012
    Review
  8. [Intensive medical care problems of hemato-oncological patients].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2012
    Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

B SchönhoferAbteilung für Pneumologie und internistische Intensivmedizin, Krankenhaus Oststadt - Heidehaus, Klinikum Region Hannover, Podbielskistr. 380, 30659 Hannover, Deutschland. Bernd.Schoenhofer@t-online.de
R Kuhlen
P Neumann
M Westhoff
C Berndt
H Sitter
Klinikum Region Hannover · DEEvangelisches Krankenhaus Göttingen-Weende · DEHelios Hospital Berlin-Buch · DELungenklinik Hemer · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScientific evidence is accumulating that non-invasive ventilation (NIV) may be beneficial for different patient groups with acute respiratory insufficiency (ARI). The aim of the new S3 guidelines is to propagate evidence-based knowledge about the indications and limitations of NIV in clinical practice.

methodsA total of 28 experts from 12 German medical societies were involved in the process of development of the present guidelines. These experts systematically analyzed approximately 2,900 publications. Finally, the recommendations were discussed and approved in two consensus conferences.

resultsIn hypercapnic ARI, NIV reduces the length of stay and mortality during intensive care treatment [grade A recommendation (A)]. Patients with cardiopulmonary edema should be treated with continuous positive airway pressure (CPAP) or NIV (A). For immunocompromized patients with ARI, NIV reduces the mortality (A). In patients with postextubation respiratory failure and during weaning from mechanical ventilation, NIV reduces the risk of reintubation (A). For patients who decline to be ventilated invasively, NIV may be an acceptable alternative (B). Non-invasive ventilation can also successfully be used in pediatric patients with ARI caused by different reasons (C). In acute respiratory distress syndrome (ARDS) NIV cannot generally be recommended because the failure rate is relatively high.

conclusionNon-invasive ventilation is still not as widely implemented in clinical medicine as would be expected on the basis of the scientific literature. The aim of the present guidelines is to further propagate NIV for the treatment of ARI.

Indexed as

Acute DiseaseAdultChildConsensus Statements as TopicContinuous Positive Airway PressureCritical CareGermanyGuidelines as TopicHospital MortalityHumansHypercapniaImmunocompromised HostLength of StayMonitoring, PhysiologicRespiration, ArtificialRespiratory Insufficiency

Identifiers

PMID18989651
OpenAlexW2065781167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.