ArticlePLoS genetics2008
The evolutionary dynamics of the lion Panthera leo revealed by host and viral population genomics.
Article in PLoS genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
46 citing papers in PubMed, 120 citations in OpenAlex.
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- Skull morphology analysis suggests the extinct Cape lion, Panthera leo melanochaita (Smith, 1842), is not distinctive.Scientific reports · 2024Article
- The Addis Ababa Lions: Whole-Genome Sequencing of a Rare and Precious Population.Genome biology and evolution · 2024Article
- Whole genome sequencing and the application of a SNP panel reveal primary evolutionary lineages and genomic variation in the lion (Panthera leo).BMC genomics · 2022Article
- Genetic guidelines for translocations: Maintaining intraspecific diversity in the lion (Evolutionary applications · 2022Article
- Equal contributions of feline immunodeficiency virus and coinfections to morbidity in African lions.International journal for parasitology. Parasites and wildlife · 2021Article
- Cross-species transmission of retroviruses among domestic and wild felids in human-occupied landscapes in Chile.Evolutionary applications · 2021Article
- Puma (Animals : an open access journal from MDPI · 2021Article
- Spatiotemporal Genetic Diversity of Lions Reveals the Influence of Habitat Fragmentation across Africa.Molecular biology and evolution · 2021Article
- Article
- The role of kinship and demography in shaping cooperation amongst male lions.Scientific reports · 2020Article
- Does the virus cross the road? Viral phylogeographic patterns among bobcat populations reflect a history of urban development.Evolutionary applications · 2020Article
- The evolutionary history of extinct and living lions.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data.BMC biology · 2020Article
- Population genetic structure and habitat connectivity for jaguar (Panthera onca) conservation in Central Belize.BMC genetics · 2019Article
- Endemic infection can shape exposure to novel pathogens: Pathogen co-occurrence networks in the Serengeti lions.Ecology letters · 2019Article
- Genetic analysis of African lions (Panthera leo) in Zambia support movement across anthropogenic and geographical barriers.PloS one · 2019Article
- Microsatellite DNA analysis reveals lower than expected genetic diversity in the threatened leopard cat (Prionailurus bengalensis) in South Korea.Genes & genomics · 2018Article
- A genome-wide data assessment of the African lion (Panthera leo) population genetic structure and diversity in Tanzania.PloS one · 2018Article
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Authors and funding
20 authors at 13 institutions in 6 countries.
Funding
Abstract
The lion Panthera leo is one of the world's most charismatic carnivores and is one of Africa's key predators. Here, we used a large dataset from 357 lions comprehending 1.13 megabases of sequence data and genotypes from 22 microsatellite loci to characterize its recent evolutionary history. Patterns of molecular genetic variation in multiple maternal (mtDNA), paternal (Y-chromosome), and biparental nuclear (nDNA) genetic markers were compared with patterns of sequence and subtype variation of the lion feline immunodeficiency virus (FIV(Ple)), a lentivirus analogous to human immunodeficiency virus (HIV). In spite of the ability of lions to disperse long distances, patterns of lion genetic diversity suggest substantial population subdivision (mtDNA Phi(ST) = 0.92; nDNA F(ST) = 0.18), and reduced gene flow, which, along with large differences in sero-prevalence of six distinct FIV(Ple) subtypes among lion populations, refute the hypothesis that African lions consist of a single panmictic population. Our results suggest that extant lion populations derive from several Pleistocene refugia in East and Southern Africa ( approximately 324,000-169,000 years ago), which expanded during the Late Pleistocene ( approximately 100,000 years ago) into Central and North Africa and into Asia. During the Pleistocene/Holocene transition ( approximately 14,000-7,000 years), another expansion occurred from southern refugia northwards towards East Africa, causing population interbreeding. In particular, lion and FIV(Ple) variation affirms that the large, well-studied lion population occupying the greater Serengeti Ecosystem is derived from three distinct populations that admixed recently.
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Registered trials
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