ArticlePloS one2008
Predicting adaptive behavior in the environment from central nervous system dynamics.
Article in PloS one, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Motor priming is associated with widespread recruitment into neural ensembles and more rapid ensemble transitions.iScience · 2026Article
- Variable task switching in the feeding network ofJournal of neurophysiology · 2023Article
- Persistent modulatory actions and task switching in the feeding network of Aplysia.Current opinion in neurobiology · 2023Review
- Convergent effects of neuropeptides on the feeding central pattern generator ofJournal of neurophysiology · 2022Article
- An Anticipatory Circuit Modification That Modifies Subsequent Task Switching.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- The Complement of Projection Neurons Activated Determines the Type of Feeding Motor Program inFrontiers in neural circuits · 2021Article
- Network Degeneracy and the Dynamics of Task Switching in the Feeding Circuit inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Cellular Effects of Repetition Priming in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Consequences of degeneracy in network function.Current opinion in neurobiology · 2016Review
- Latent modulation: a basis for non-disruptive promotion of two incompatible behaviors by a single network state.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- The stomatogastric nervous system as a model for studying sensorimotor interactions in real-time closed-loop conditions.Frontiers in computational neuroscience · 2012Article
- Towards a scientific concept of free will as a biological trait: spontaneous actions and decision-making in invertebrates.Proceedings. Biological sciences · 2011Review
- Repetition priming of motoneuronal activity in a small motor network: intercellular and intracellular signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Composite modulatory feedforward loop contributes to the establishment of a network state.Journal of neurophysiology · 2010Article
- Distinct mechanisms produce functionally complementary actions of neuropeptides that are structurally related but derived from different precursors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Neuromechanical simulation.Frontiers in behavioral neuroscience · 2010Article
- Motor outputs in a multitasking network: relative contributions of inputs and experience-dependent network states.Journal of neurophysiology · 2009Article
- Distinct inhibitory neurons exert temporally specific control over activity of a motoneuron receiving concurrent excitation and inhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Perception and hierarchical dynamics.Frontiers in neuroinformatics · 2009Article
- Cycle-to-cycle variability as an optimal behavioral strategy.Neurocomputing · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
To generate adaptive behavior, the nervous system is coupled to the environment. The coupling constrains the dynamical properties that the nervous system and the environment must have relative to each other if adaptive behavior is to be produced. In previous computational studies, such constraints have been used to evolve controllers or artificial agents to perform a behavioral task in a given environment. Often, however, we already know the controller, the real nervous system, and its dynamics. Here we propose that the constraints can also be used to solve the inverse problem--to predict from the dynamics of the nervous system the environment to which they are adapted, and so reconstruct the production of the adaptive behavior by the entire coupled system. We illustrate how this can be done in the feeding system of the sea slug Aplysia. At the core of this system is a central pattern generator (CPG) that, with dynamics on both fast and slow time scales, integrates incoming sensory stimuli to produce ingestive and egestive motor programs. We run models embodying these CPG dynamics--in effect, autonomous Aplysia agents--in various feeding environments and analyze the performance of the entire system in a realistic feeding task. We find that the dynamics of the system are tuned for optimal performance in a narrow range of environments that correspond well to those that Aplysia encounter in the wild. In these environments, the slow CPG dynamics implement efficient ingestion of edible seaweed strips with minimal sensory information about them. The fast dynamics then implement a switch to a different behavioral mode in which the system ignores the sensory information completely and follows an internal "goal," emergent from the dynamics, to egest again a strip that proves to be inedible. Key predictions of this reconstruction are confirmed in real feeding animals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.