Evidence map›Paper›PMID 18989221›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2008

A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with men.

Stephen F Morin, Starley B Shade, Wayne T Steward, Adam W Carrico, Robert H Remien, Mary Jane Rotheram-Borus, Jeffrey A Kelly, Edwin D Charlebois, Mallory O Johnson, Margaret A Chesney and 1 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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  8. Project enhance: a randomized controlled trial of an individualized HIV prevention intervention for HIV-infected men who have sex with men conducted in a primary care setting.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Stephen F MorinCenter for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA 94105, USA. steve.morin@ucsf.edu
Starley B Shade
Wayne T Steward
Adam W Carrico
Robert H Remien
Mary Jane Rotheram-Borus
Jeffrey A Kelly
Edwin D Charlebois
Mallory O Johnson
Margaret A Chesney
Healthy Living Project Team
University of California, San Francisco · USSan Francisco AIDS Foundation · USMedical College of Wisconsin · USNew York Psychoanalytic Society and Institute · USUniversity of California, Los Angeles · US

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057615 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY J · 2001 to 2004
$5.2M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057636 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE · PI EHRHARDT, ANKE A · 2001 to 2004
$3.5M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057616 · NIMH · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI MORIN, STEPHEN F · 2001 to 2004
$2.9M
HEALTH RELATED INTERVENTIONS FOR PERSONS LIVING WITH HIVU10MH057631 · NIMH · MEDICAL COLLEGE OF WISCONSIN · PI KELLY, JEFFREY A. · 2001 to 2004
$2.2M
NIMH NIH HHS P30 MH043520NIMH NIH HHS U10 MH057615NIMH NIH HHS U10MH057615NIMH NIH HHS U10 MH057616NIMH NIH HHS U10MH057616NIMH NIH HHS U10 MH057631NIMH NIH HHS U10MH057631NIMH NIH HHS U10 MH057636NIMH NIH HHS U10MH057636
6 · The paper itself

Abstract

objectiveTo examine factors that explain the effect of a cognitive-behavioral intervention on reductions in HIV transmission risk among HIV-infected men who have sex with men (MSM).

methodOf the 1910 HIV-infected MSM screened, 616 participants considered to be at risk of transmitting HIV were randomized to a 15-session, individually delivered cognitive-behavioral intervention (n=301) or a wait-list control (n=315).

resultsConsistent with previous intent-to-treat findings, there was an overall reduction in transmission risk acts among MSM in both intervention and control arms, with significant intervention effects observed at the 5-, 10-, 15-, and 20-month assessments (risk ratios=0.78, 0.62, 0.48, and 0.38, respectively). These intervention-related decreases in HIV transmission risk acts seemed to be partially due to sustained serosorting practices. MSM in the intervention condition reported a significantly greater proportion of sexual partners who were HIV infected at the 5- and 10-month assessments (risk ratios=1.14 and 1.18).

conclusionsThe Healthy Living Project, a cognitive-behavioral intervention, is efficacious in reducing transmission risk acts among MSM. This seems to have been due in large part to the fact that MSM in the intervention condition reported sustained serosorting practices.

Indexed as

Health Knowledge, Attitudes, PracticeHomosexuality, MaleSafe SexAdultHIV InfectionsHumansMaleRisk FactorsRisk-TakingSexual Partners

Identifiers

PMID18989221
PMCPMC2659703
OpenAlexW1992704130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.