Evidence map›Paper›PMID 18987987›Full record

ReviewJournal of inherited metabolic disease2008

The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review.

M M C Wamelink, E A Struys, C Jakobs

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of inherited metabolic disease, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed.

  1. Article
  2. Article
  3. Nonoxidative pentose phosphate pathway regulates CD8Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Antifungal activity of the culture filtrate ofFrontiers in microbiology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Daily Brain Metabolic Rhythms of Wild Nocturnal Bats.International journal of molecular sciences · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article

80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

M M C WamelinkMetabolic Unit, Department of Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. M.Wamelink@vumc.nl
E A Struys
C Jakobs

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent discovery of two defects (ribose-5-phosphate isomerase deficiency and transaldolase deficiency) in the reversible part of the pentose phosphate pathway (PPP) has stimulated interest in this pathway. In this review we describe the functions of the PPP, its relation to other pathways of carbohydrate metabolism and an overview of the metabolic defects in the reversible part of the PPP.

Indexed as

MutationGlycolysisHumansHypoxiaMetabolism, Inborn ErrorsModels, BiologicalNADPNeoplasmsOxygenPentose Phosphate PathwayPhenotypeRiboseTransaldolaseNADPOxygenRiboseTransaldolase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.