ArticleAnnals of biomedical engineering2009
Hemodynamic performance of stage-2 univentricular reconstruction: Glenn vs. hemi-Fontan templates.
Article in Annals of biomedical engineering, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Fontan Surgical Planning: Numerical Simulations Reveal Efficient Geometries Predicting Post-Surgical Outcomes.Brazilian journal of cardiovascular surgery · 2025Article
- Hemi-Fontan and bidirectional Glenn operations result in flow-mediated viscous energy loss at the time of stage II palliation.JTCVS open · 2023Article
- A computational study of aortic reconstruction in single ventricle patients.Biomechanics and modeling in mechanobiology · 2023Article
- In-Silico and In-Vitro Analysis of the Novel Hybrid Comprehensive Stage II Operation for Single Ventricle Circulation.Bioengineering (Basel, Switzerland) · 2023Article
- Imaging of Fontan-associated liver disease.Pediatric radiology · 2020Review
- Numerical Simulation of Hemodynamics in Two Models for Total Anomalous Pulmonary Venous Connection Surgery.Frontiers in physiology · 2020Article
- Computational Pre-surgical Planning of Arterial Patch Reconstruction: Parametric Limits and In Vitro Validation.Annals of biomedical engineering · 2018Article
- Preoperative single ventricle function determines early outcome after second-stage palliation of single ventricle heart.Cardiovascular ultrasound · 2017Article
- Tetralogy of Fallot Surgical Repair: Shunt Configurations, Ductus Arteriosus and the Circle of Willis.Cardiovascular engineering and technology · 2017Article
- Three-dimensional Printing in Developing Countries.Plastic and reconstructive surgery. Global open · 2015Article
- A multiscale model for the study of cardiac biomechanics in single-ventricle surgeries: a clinical case.Interface focus · 2015Article
- An integrated approach to patient-specific predictive modeling for single ventricle heart palliation.Computer methods in biomechanics and biomedical engineering · 2014Article
- Simulation based planning of surgical interventions in pediatric cardiology.Physics of fluids (Woodbury, N.Y. : 1994) · 2013Article
- Fontan conversion templates: patient-specific hemodynamic performance of the lateral tunnel versus the intraatrial conduit with fenestration.Pediatric cardiology · 2013Article
- Considerations for numerical modeling of the pulmonary circulation--a review with a focus on pulmonary hypertension.Journal of biomechanical engineering · 2013Review
- Article
- Computer-Aided Patient-Specific Coronary Artery Graft Design Improvements Using CFD Coupled Shape Optimizer.Cardiovascular engineering and technology · 2011Article
- 3D printing based on imaging data: review of medical applications.International journal of computer assisted radiology and surgery · 2010Article
- Larger aortic reconstruction corresponds to diminished left pulmonary artery size in patients with single-ventricle physiology.The Journal of thoracic and cardiovascular surgery · 2010Article
- Patient-specific surgical planning and hemodynamic computational fluid dynamics optimization through free-form haptic anatomy editing tool (SURGEM).Medical & biological engineering & computing · 2008Article
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
Flow structures, hemodynamics and the hydrodynamic surgical pathway resistances of the final stage functional single ventricle reconstruction, namely the total cavopulmonary connection (TCPC) anatomy, have been investigated extensively. However, the second stage surgical anatomy (i.e., bi-directional Glenn or hemi-Fontan template) has received little attention. We thus initiated a multi-faceted study, involving magnetic resonance imaging (MRI), phase contrast MRI, computational and experimental fluid dynamics methodologies, focused on the second stage of the procedure. Twenty three-dimensional computer and rapid prototype models of 2nd stage TCPC anatomies were created, including idealized parametric geometries (n = 6), patient-specific anatomies (n = 7), and their virtual surgery variant (n = 7). Results in patient-specific and idealized models showed that the Glenn connection template is hemodynamically more efficient with (83% p = 0.08 in patient-specific models and 66% in idealized models) lower power losses compared to hemi-Fontan template, respectively, due to its direct end-to-side anastomosis. Among the several secondary surgical geometrical features, stenosis at the SVC anastomosis or in pulmonary branches was found to be the most critical parameter in increasing the power loss. The pouch size and flare shape were found to be less significant. Compared to the third stage surgery the hydrodynamic resistance of the 2nd stage is considerably lower (both in idealized models and in anatomical models at MRI resting conditions) for both hemi- and Glenn templates. These results can impact the surgical design and planning of the staged TCPC reconstruction.
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