Evidence map›Paper›PMID 18987912›Full record

ArticleCurrent microbiology2009

Ers controls glycerol metabolism in Enterococcus faecalis.

Eliette Riboulet-Bisson, Axel Hartke, Yanick Auffray, Jean-Christophe Giard

Abstract read
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Article in Current microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Eliette Riboulet-BissonLaboratoire de Microbiologie de l'Environnement, EA 956 soutenue par l'INRA, IFR 146, Université de Caen, 14032 Caen Cedex, France.
Axel Hartke
Yanick Auffray
Jean-Christophe Giard
Institut National de la Recherche Agronomique · MAUniversité de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ers is a pleiotropic transcriptional regulator in Enterococcus faecalis, an opportunistic bacterium. The authors have already shown that this protein is important for survival against oxidative stress and within macrophages as well as for survival of mice, and that Ers also is involved in the regulation of citrate and arginine metabolisms. The current study highlights the involvement of Ers also in the regulation of glycerol metabolism. The results suggest that EF0082, a known member of the Ers regulon encoding a major facilitator family transporter, may be able to transport glycerol. Moreover, the study demonstrates that Ers acts as a positive regulator of the glpKOF operon encoding glycerol kinase, glycerol-3-phosphate oxidase, and glycerol transport facilitator proteins.

Indexed as

Bacterial ProteinsEnterococcus faecalisGene Expression Regulation, BacterialGlycerolGlycerol KinaseGlycerolphosphate DehydrogenaseOperonRegulonTranscription FactorsBacterial ProteinsGlycerolglycerol-3-phosphate oxidaseGlycerol KinaseGlycerolphosphate DehydrogenaseTranscription Factors

Identifiers

PMID18987912
OpenAlexW2003689093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.