ArticleProtoplasma1999
Is 2,3-butanedione monoxime an effective inhibitor of myosin-based activities in plant cells?
Article in Protoplasma, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
12 citing papers in PubMed, 45 citations in OpenAlex.
- Myosins XI Are Involved in Exocytosis of Cellulose Synthase Complexes.Plant physiology · 2019Article
- Arabidopsis myosin XI: a motor rules the tracks.Plant physiology · 2014Article
- Rapid severing and motility of chloroplast-actin filaments are required for the chloroplast avoidance response in Arabidopsis.The Plant cell · 2013Article
- Actin-dependent deposition of putative endosomes and endoplasmic reticulum during early stages of wound healing in characean internodal cells.Plant biology (Stuttgart, Germany) · 2011Article
- Inhibitors of myosin, but not actin, alter transport through Tradescantia plasmodesmata.Protoplasma · 2011Article
- Structure and dynamics of an Arp2/3 complex-independent component of the lamellipodial actin network.Cell motility and the cytoskeleton · 2009Article
- Actin filament dynamics are dominated by rapid growth and severing activity in the Arabidopsis cortical array.The Journal of cell biology · 2009Article
- Multidimensional fluorescence microscopy of multiple organelles in Arabidopsis seedlings.Plant methods · 2008Article
- Truncated myosin XI tail fusions inhibit peroxisome, Golgi, and mitochondrial movement in tobacco leaf epidermal cells: a genetic tool for the next generation.Journal of experimental botany · 2008Article
- Myosin inhibitors block accumulation movement of chloroplasts in Arabidopsis thaliana leaf cells.Protoplasma · 2007Article
- Cell wall pectins and xyloglucans are internalized into dividing root cells and accumulate within cell plates during cytokinesis.Protoplasma · 2005Article
- 2,3-Butanedione monoxime (BDM) as a myosin inhibitor.Journal of muscle research and cell motility · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effectiveness of 2,3-butanedione monoxime (BDM) as an inhibitor of plant myosins has been investigated. Three myosin-dependent motility phenomena in plants, namely cytoplasmic streaming in Chara corallina, light-dependent chloroplast repositioning in Elodea sp., and brefeldin A(BFA)-induced Golgi membrane dynamics in wheat (Triticum aestivum L. cv. Kite) root-tip cells were investigated. All three processes were inhibited by the sulfhydryl-modifying agent N-ethylmalemide (NEM), indicating the probable involvement of myosin as the motor protein in each case. However, none of these myosin-dependent processes were inhibited by BDM at concentrations as high as 20 mM in some instances. These results therefore question the general usefulness of BDM as an inhibitor of myosin-based activities in plant cells.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.